PCIDB

KCF-S cluster No. 4529 (2 metabolites)

Plant Species

Cumulative plant class count

class name count
asterids 1

Cumulative family count

class name count
Xylariaceae 1
Asteraceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00048593 External link 512 7-Amino-4-methylcoumarin
CHEMBL270672
C028743
20 / 19 / 15
C00049093 External link 512 5-Methylcoumarin

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00048593 3 / 0
P04062 Glucosylceramidase Enzyme C00048593 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00048593 1 / 1
P29466 Caspase-1 C14 C00048593 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00048593 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00048593 1 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00048593 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00048593 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00048593 1 / 2
Q92830 Histone acetyltransferase KAT2A Enzyme C00048593 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00048593 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00048593 0 / 0
P06280 Alpha-galactosidase A Enzyme C00048593 1 / 1
Q16790 Carbonic anhydrase 9 Lyase C00048593 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00048593 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00048593 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00048593 0 / 0
P55210 Caspase-7 C14 C00048593 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00048593 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00048593 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#119900 Digital clubbing, isolated congenital P15428
#301500 Fabry disease P06280
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#143500 Gilbert syndrome P22310
#232300 Glycogen storage disease ii P10253
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (15)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)