PCIDB

KNApSAcK Metabolite C00048708

Metabolite

KNApSAcK Entry

id C00048708
Name Eupomatenoid 6
CAS RN 41744-26-7
Standard InChI InChI=1S/C18H16O2/c1-3-4-13-5-10-17-16(11-13)12(2)18(20-17)14-6-8-15(19)9-7-14/h3-11,19H,1-2H3/b4-3+
Standard InChI (Main Layer) InChI=1S/C18H16O2/c1-3-4-13-5-10-17-16(11-13)12(2)18(20-17)14-6-8-15(19)9-7-14/h3-11,19H,1-2H3

Cluster

Phytochemical cluster
KCF-S cluster No. 3329

Link

ChEMBL

By standard InChI CHEMBL463574
By standard InChI Main Layer CHEMBL463574

KEGG

By LinkDB

CTD

By CAS RN C452812

Species

Summary

Plant class

class name count
Magnoliophyta 1

Family

family name count
Piperaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Piper regnellii 13215 Piperaceae Magnoliophyta Viridiplantae

Human Protein / Gene in interaction

14 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL463574 CHEMBL1613842 (1)
4 / 2
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL463574 CHEMBL2149156 (1)
0 / 0
O14684 Prostaglandin E synthase Enzyme CHEMBL463574 CHEMBL2149157 (1)
0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase CHEMBL463574 CHEMBL2148588 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL463574 CHEMBL1614458 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL463574 CHEMBL2149029 (1)
0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL463574 CHEMBL2148591 (1)
5 / 3
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL463574 CHEMBL1614521 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL463574 CHEMBL1614038 (1)
2 / 2
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL463574 CHEMBL1614250 (1) CHEMBL1614421 (1)
CHEMBL1614502 (1)
4 / 3
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 CHEMBL463574 CHEMBL2148590 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL463574 CHEMBL1613914 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL463574 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL463574 CHEMBL1614257 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#119900 Digital clubbing, isolated congenital P15428
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#601665 Obesity P37231
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (17)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)