KNApSAcK Metabolite C00007057
Metabolite
KNApSAcK Entry
| id | C00007057 |
|---|---|
| Name | Licochalcone A |
| CAS RN | 58749-22-7 |
| Standard InChI | InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ |
| Standard InChI (Main Layer) | InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 3383 |
Link
ChEMBL
| By standard InChI | CHEMBL139702 |
|---|---|
| By standard InChI Main Layer | CHEMBL139702 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C070840 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 5 |
Family
| family name | count |
|---|---|
| Fabaceae | 4 |
| Euphorbiaceae | 1 |
List (5)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Euphorbia helioscopia L. | 154990 | Euphorbiaceae | rosids | Viridiplantae |
| Glycyrrhiza eurycarpa | 372983 | Fabaceae | rosids | Viridiplantae |
| Glycyrrhiza glabra | 49827 | Fabaceae | rosids | Viridiplantae |
| Glycyrrhiza inflata | 74614 | Fabaceae | rosids | Viridiplantae |
| Spatholobus suberectus | 455371 | Fabaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
1 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | CHEMBL139702 |
CHEMBL1041717
(1)
CHEMBL1781409
(1)
|
0 / 0 |
CTD interaction (2)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C070840 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | licochalcone A inhibits the reaction [IL1B protein results in increased abundance of Dinoprost] |
decreases reaction
/ increases abundance |
protein |
16354411
|
| C070840 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | licochalcone A inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone] |
decreases reaction
/ increases abundance |
protein |
16354411
|