Euphorbia helioscopia L.

• Index
• Plant Species
• Metabolite list (17)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Euphorbia helioscopia L.
Genus	Euphorbia
Family	Euphorbiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Euphorbia helioscopia
Linked NCBI taxonomy ID	154990
Linked level	species

Family

Family in NCBI taxonomy	Euphorbiaceae
ID	3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (17)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00009434	Glabrone / Eurycarpin B	CHEMBL600457		1 / 5 / 3		No. 24	No. 15
C00029518	4',5,7-Trihydroxyflavanone / 5,7,4'-Trihydroxyflavanone	CHEMBL9352 CHEMBL32571		57 / 46 / 40		No. 25	No. 14
C00006938	Licochalcone B					No. 92	No. 13
C00030506	Icariside B2 / (-)-Icariside B2					No. 153
C00030468	Hemistepsin					No. 206	No. 38
C00030234	Euphornin C					No. 757	No. 41
C00030232	Euphornin	CHEMBL499921				No. 757	No. 41
C00030233	Euphornin B	CHEMBL463643				No. 757	No. 41
C00030231	Euphoheliosnoid D					No. 757	No. 41
C00030235	Euphoscopin A					No. 757	No. 41
C00030239	Euphoscopin J					No. 757	No. 41
C00030237	Euphoscopin C	CHEMBL506068				No. 757	No. 41
C00030238	Euphoscopin F					No. 757	No. 41
C00030236	Euphoscopin B					No. 757	No. 41
C00030230	Euphohelioscopin A					No. 1267	No. 41
C00030467	Helioscopinolide B	CHEMBL469645 CHEMBL451142		1 / 0 / 0		No. 2372
C00007057	Licochalcone A	CHEMBL139702	C070840	1 / 0 / 0	1 / 0	No. 3383

Human Protein / Gene in interactions

57 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00007057 C00029518 C00030467	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00009434 C00029518	5 / 3
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00029518	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00029518	3 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00029518	1 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00029518	1 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00029518	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00029518	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00029518	0 / 3
P04062	Glucosylceramidase	Enzyme	C00029518	6 / 4
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00029518	0 / 0
P62158	Calmodulin	Unclassified protein	C00029518	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00029518	1 / 1
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00029518	0 / 0
P08183	Multidrug resistance protein 1	drug	C00029518	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00029518	0 / 1
P24941	Cyclin-dependent kinase 2	Cdc2	C00029518	0 / 0
P24864	G1/S-specific cyclin-E1	Other cytosolic protein	C00029518	0 / 2
O75828	Carbonyl reductase [NADPH] 3	Enzyme	C00029518	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00029518	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00029518	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00029518	1 / 1
P16152	Carbonyl reductase [NADPH] 1	Enzyme	C00029518	0 / 0
O75496	Geminin	Unclassified protein	C00029518	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00029518	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00029518	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00029518	0 / 1
P15121	Aldose reductase	Enzyme	C00029518	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00029518	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029518	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00029518	0 / 1
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00029518	2 / 2
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00029518	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00029518	4 / 4
P04745	Alpha-amylase 1	Enzyme	C00029518	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00029518	2 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00029518	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00029518	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00029518	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00029518	1 / 1
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00029518	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00029518	0 / 0
P03372	Estrogen receptor	NR3A1	C00029518	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00029518	1 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00029518	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00029518	1 / 1
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00029518	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00029518	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00029518	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00029518	5 / 1
P10275	Androgen receptor	NR3C4	C00029518	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00029518	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00029518	0 / 0
P49888	Estrogen sulfotransferase	Enzyme	C00029518	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00029518	1 / 1
O00255	Menin	Unclassified protein	C00029518	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00029518	1 / 2

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00007057

Related Diseases

Diseases related to proteins in ChEMBL interactions