Metabolite

KNApSAcK Entry

id C00007284
Name Copro'gen / Coproporphyrinogen III
CAS RN 2624-63-7
Standard InChI InChI=1S/C36H44N4O8/c1-17-21(5-9-33(41)42)29-14-27-19(3)22(6-10-34(43)44)30(39-27)15-28-20(4)24(8-12-36(47)48)32(40-28)16-31-23(7-11-35(45)46)18(2)26(38-31)13-25(17)37-29/h37-40H,5-16H2,1-4H3,(H,41,42)(H,43,44)(H,45,46)(H,47,48)
Standard InChI (Main Layer) InChI=1S/C36H44N4O8/c1-17-21(5-9-33(41)42)29-14-27-19(3)22(6-10-34(43)44)30(39-27)15-28-20(4)24(8-12-36(47)48)32(40-28)16-31-23(7-11-35(45)46)18(2)26(38-31)13-25(17)37-29/h37-40H,5-16H2,1-4H3,(H,41,42)(H,43,44)(H,45,46)(H,47,48)

Cluster

Phytochemical cluster
KCF-S cluster No. 5144

Link

ChEMBL

By standard InChI CHEMBL1231891
By standard InChI Main Layer CHEMBL1231891

KEGG

By LinkDB C03263

CTD

By CAS RN C028026

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1
Rhodobacteraceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Rhodobacter sphaeroides 1063 Rhodobacteraceae Bacteria

Human Protein / Gene in interaction

1 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P36551 Coproporphyrinogen-III oxidase, mitochondrial Enzyme CHEMBL1231891 CHEMBL1676173 (1)
1 / 1

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C028026 1371 CPOX
CPO
CPX
HCP
coproporphyrinogen oxidase (EC:1.3.3.3) CPOX protein results in decreased carboxylation of coproporphyrinogen III decreases carboxylation
protein 19339664
C028026 1371 CPOX
CPO
CPX
HCP
coproporphyrinogen oxidase (EC:1.3.3.3) Mercury inhibits the reaction [CPOX protein results in decreased carboxylation of coproporphyrinogen III] decreases carboxylation
/ decreases reaction
protein 19339664

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#121300 Coproporphyria, hereditary; hcp P36551

KEGG DISEASE (1)

KEGG disease name UniProt
H00202 Hepatic porphyria P36551 (related)