PCIDB

KNApSAcK Metabolite C00007391

Metabolite

KNApSAcK Entry

id C00007391
Name alpha-D-Galactose 1-phosphate
CAS RN 2255-14-3
Standard InChI InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3+,4+,5-,6-/m1/s1
Standard InChI (Main Layer) InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)

Cluster

Phytochemical cluster
KCF-S cluster No. 713

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL291890 CHEMBL67622 CHEMBL1159526 CHEMBL1741538

KEGG

By LinkDB C03384

CTD

By CAS RN C029973

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1
Enterobacteriaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Escherichia coli K12 83333 Enterobacteriaceae Bacteria

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1741538 CHEMBL1741321 (1)
1 / 0
P10323 Acrosin S1A CHEMBL1159526 CHEMBL639764 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1741538 CHEMBL1741325 (1)
0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1741538 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1741538 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1741538 CHEMBL1741324 (1)
0 / 1

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C029973 2584 GALK1
GALK
GK1
galactokinase 1 (EC:2.7.1.6) [Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein] which results in decreased abundance of galactose-1-phosphate affects binding
/ decreases abundance
/ decreases activity
protein 20696150
C029973 2584 GALK1
GALK
GK1
galactokinase 1 (EC:2.7.1.6) [GALK1 protein results in increased metabolism of Galactose] which results in increased abundance of galactose-1-phosphate increases abundance
/ increases metabolic processing
protein 20696150

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D005693 C029973 Galactosemias marker/mechanism
20696150