KNApSAcK Metabolite C00007446
Metabolite
KNApSAcK Entry
| id | C00007446 |
|---|---|
| Name | PAPS / 3'-phosphoadenosine 5'-phosphosulfate |
| CAS RN | 482-67-7 |
| Standard InChI | InChI=1S/C10H15N5O13P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24)/t4-,6+,7?,10-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C10H15N5O13P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1201 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C00053 |
|---|
CTD
| By CAS RN | D010724 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Brassicaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (16)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D010724 | 10 |
NAT2
AAC2 NAT-2 PNAT |
N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5) | [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] |
affects cotreatment
/ increases activity / increases reaction / increases reduction |
protein |
20545351
|
| D010724 | 1728 |
NQO1
DHQU DIA4 DTD NMOR1 NMORI QR1 |
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone |
affects cotreatment
/ increases activity / increases reduction |
protein |
20545351
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | 2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | Halogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone |
affects cotreatment
/ increases activity / increases reduction |
protein |
20545351
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | pentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | Pentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | SULT1A1 protein results in increased sulfation of Phosphoadenosine Phosphosulfate |
increases sulfation
|
protein |
11425650
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | tribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
16601080
|
| D010724 | 6799 |
SULT1A2
HAST4 P-PST ST1A2 STP2 TSPST2 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) | [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] |
affects cotreatment
/ increases activity / increases reaction / increases reduction |
protein |
20545351
|
| D010724 | 6818 |
SULT1A3
HAST HAST3 M-PST ST1A3/ST1A4 ST1A5 STM TL-PST |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) | SULT1A3 protein results in increased sulfation of Phosphoadenosine Phosphosulfate |
increases sulfation
|
protein |
11425650
|
| D010724 | 6822 |
SULT2A1
DHEA-ST DHEAS HST ST2 ST2A1 ST2A3 STD hSTa |
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) | celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol] |
affects cotreatment
/ affects reaction / affects sulfation |
protein |
15483193
|
| D010724 | 6822 |
SULT2A1
DHEA-ST DHEAS HST ST2 ST2A1 ST2A3 STD hSTa |
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) | [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol |
affects cotreatment
/ affects sulfation |
protein |
15483193
|
| D010724 | 6822 |
SULT2A1
DHEA-ST DHEAS HST ST2 ST2A1 ST2A3 STD hSTa |
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) | SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] |
affects cotreatment
/ affects metabolic processing |
protein |
15483193
|