KNApSAcK Metabolite C00007462
Metabolite
KNApSAcK Entry
| id | C00007462 |
|---|---|
| Name | Coenzyme A / Palmityl-CoA / Palmitoyl CoA |
| CAS RN | 1763-10-6 |
| Standard InChI | InChI=1S/C37H66N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52)/t26-,30-,31-,32+,36-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C37H66N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52) |
Cluster
| Phytochemical cluster | No. 6 |
|---|---|
| KCF-S cluster | No. 461 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C00154 |
|---|
CTD
| By CAS RN | D010171 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Brassicaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (8)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D010171 | 8694 |
DGAT1
ARAT ARGP1 DGAT |
diacylglycerol O-acyltransferase 1 (EC:2.3.1.20 2.3.1.76) | DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] |
affects cotreatment
/ increases metabolic processing |
protein |
16214399
|
| D010171 | 2938 |
GSTA1
GST2 GSTA1-1 GTH1 |
glutathione S-transferase alpha 1 (EC:2.5.1.18) | Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein |
affects binding
/ decreases activity |
protein |
10542059
|
| D010171 | 3172 |
HNF4A
HNF4 HNF4a7 HNF4a8 HNF4a9 HNF4alpha MODY MODY1 NR2A1 NR2A21 TCF TCF14 |
hepatocyte nuclear factor 4, alpha | Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA |
decreases expression
|
mRNA |
17992261
|
| D010171 | 3172 |
HNF4A
HNF4 HNF4a7 HNF4a8 HNF4a9 HNF4alpha MODY MODY1 NR2A1 NR2A21 TCF TCF14 |
hepatocyte nuclear factor 4, alpha | Palmitoyl Coenzyme A results in decreased expression of HNF4A protein |
decreases expression
|
protein |
17992261
|
| D010171 | 5465 |
PPARA
NR1C1 PPAR PPARalpha hPPAR |
peroxisome proliferator-activated receptor alpha | Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein |
affects binding
/ increases activity |
protein |
11139385
|
| D010171 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein |
affects binding
/ increases activity |
protein |
11139385
|
| D010171 | 6462 |
SHBG
ABP SBP TEBG |
sex hormone-binding globulin | Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA |
decreases expression
|
mRNA |
17992261
|
| D010171 | 6462 |
SHBG
ABP SBP TEBG |
sex hormone-binding globulin | Palmitoyl Coenzyme A results in decreased expression of SHBG protein |
decreases expression
|
protein |
17992261
|