KCF-S cluster No. 461 (17 metabolites)

Corresponding Phytochemical cluster No. 6

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (17)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	12
Liliopsida	3

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Cumulative family count

class name	count
Brassicaceae	12
Enterobacteriaceae	7
Pseudomonadaceae	3
Poaceae	3

KEGG BRITE br08003

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Categories (5)

br08003 Category	# of metabolite
Others	1
Coniferyl alcohol derivatives	2
Paracoumaryl alcohol derivatives	1
Caffeate derivatives	1
Sinapate derivatives	1

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metabolites link (6)

br08003 Category	KEGG ID	KNApSAcK ID
Others	C00540	C00007263
Coniferyl alcohol derivatives	C00406	C00007264
Paracoumaryl alcohol derivatives	C00223	C00007280
Caffeate derivatives	C00323	C00007281
Sinapate derivatives	C00411	C00007283
Coniferyl alcohol derivatives	C12203	C00007361

Metabolite list (17)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00007257	3'-Dephospho-CoA		C015787
C00007258	D-Coenzyme A / Coenzyme ASH	CHEMBL1213327 CHEMBL1623949	D003065	4 / 2 / 2
C00007259	Acetyl-CoA		D000105		4 / 0
C00007260	Malonyl CoA		D008316
C00007263	Cinnamoyl-CoA
C00007264	Feruloyl-CoA
C00007269	Acetoacetyl-CoA		C010667
C00007270	3-Hydroxy-3-methylglutaryl CoA	CHEMBL1794644	C008047
C00007280	4-Coumaroyl-CoA / p-Coumaroyl-CoA	CHEMBL250086
C00007281	Caffeoyl-CoA		C058645
C00007283	Sinapoyl-CoA
C00007361	5-Hydroxyferuloyl-CoA		C090959
C00007462	Coenzyme A / Palmityl-CoA / Palmitoyl CoA		D010171		6 / 0
C00007536	Phenylacetyl-CoA / Phenylacetyl coenzyme A		C037816
C00019546	Succinyl-CoA / Succinyl coenzyme A	CHEMBL2338332	C012046	1 / 1 / 2
C00019641	2-Succinylbenzoyl-CoA / S-[2-(3-Carboxy-1-oxopropyl)benzoate] coenzyme A		C034775
C00019680	Pimeloyl-CoA / 6-Carboxyhexanoyl-CoA		C019527

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q09472	Histone acetyltransferase p300	Enzyme	C00007258	1 / 1
Q92831	Histone acetyltransferase KAT2B	Enzyme	C00007258	0 / 0
Q92993	Histone acetyltransferase KAT5	Enzyme	C00007258	0 / 0
P28329	Choline O-acetyltransferase	Enzyme	C00007258	1 / 1
Q9C0B1	Alpha-ketoglutarate-dependent dioxygenase FTO	Unclassified protein	C00019546	1 / 2

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
9	NAT1, AAC1, MNAT, NAT-1, NATI	N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00007259
10	NAT2, AAC2, NAT-2, PNAT	N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00007259
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00007259
6799	SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1)	C00007259
8694	DGAT1, ARAT, ARGP1, DGAT	diacylglycerol O-acyltransferase 1 (EC:2.3.1.20 2.3.1.76)	C00007462
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00007462
3172	HNF4A, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14	hepatocyte nuclear factor 4, alpha	C00007462
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00007462
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00007462
6462	SHBG, ABP, SBP, TEBG	sex hormone-binding globulin	C00007462

Related Diseases

Diseases related to proteins in ChEMBL interactions