PCIDB

KNApSAcK Metabolite C00007259

Metabolite

KNApSAcK Entry

id C00007259
Name Acetyl-CoA
CAS RN 72-89-9
Standard InChI InChI=1S/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)
Standard InChI (Main Layer) InChI=1S/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 461

Link

ChEMBL

By standard InChI
By standard InChI Main Layer

KEGG

By LinkDB C00024

CTD

By CAS RN D000105

Human Protein / Gene in interaction

CTD interaction (9)

compound gene gene name gene description interaction interaction type form reference
pmid
D000105 9 NAT1
AAC1
MNAT
NAT-1
NATI
N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) Acetyl Coenzyme A binds to NAT1 protein affects binding
protein 22835378
D000105 9 NAT1
AAC1
MNAT
NAT-1
NATI
N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein] decreases activity
/ decreases reaction
protein 22835378
D000105 9 NAT1
AAC1
MNAT
NAT-1
NATI
N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein] decreases activity
/ decreases reaction
protein 22835378
D000105 9 NAT1
AAC1
MNAT
NAT-1
NATI
N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone affects cotreatment
/ increases activity
/ increases reduction
protein 20545351
D000105 10 NAT2
AAC2
NAT-2
PNAT
N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5) [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] affects cotreatment
/ increases activity
/ increases reaction
/ increases reduction
protein 20545351
D000105 10 NAT2
AAC2
NAT-2
PNAT
N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5) [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] affects cotreatment
/ increases activity
/ increases reaction
/ increases reduction
protein 20545351
D000105 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] affects cotreatment
/ increases activity
/ increases reaction
/ increases reduction
protein 20545351
D000105 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone affects cotreatment
/ increases activity
/ increases reduction
protein 20545351
D000105 6799 SULT1A2
HAST4
P-PST
ST1A2
STP2
TSPST2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] affects cotreatment
/ increases activity
/ increases reaction
/ increases reduction
protein 20545351