KNApSAcK Metabolite C00007485
Metabolite
KNApSAcK Entry
| id | C00007485 |
|---|---|
| Name | Tetrachlorohydroquinone / 2,3,5,6-Tetrachlorohydroquinone |
| CAS RN | 87-87-6 |
| Standard InChI | InChI=1S/C6H2Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11/h11-12H |
| Standard InChI (Main Layer) | InChI=1S/C6H2Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11/h11-12H |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2865 |
Link
ChEMBL
| By standard InChI | CHEMBL2074639 |
|---|---|
| By standard InChI Main Layer | CHEMBL2074639 |
KEGG
| By LinkDB | C03434 |
|---|
CTD
| By CAS RN | C044578 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Sphingomonadaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Sphingobium chlorophenolicum | 46429 | Sphingomonadaceae | Bacteria |
Human Protein / Gene in interaction
1 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P08183 | Multidrug resistance protein 1 | drug | CHEMBL2074639 |
CHEMBL2076599
(1)
|
1 / 0 |
CTD interaction (3)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C044578 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | 2,3,5,6-tetrachlorohydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] |
decreases reaction
/ increases activity |
protein |
18324785
|
| C044578 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | 2,3,5,6-tetrachlorohydroquinone results in decreased expression of BCL2 protein |
decreases expression
|
protein |
11064002
|
| C044578 | 1434 |
CSE1L
CAS CSE1 XPO2 |
CSE1 chromosome segregation 1-like (yeast) | 2,3,5,6-tetrachlorohydroquinone results in decreased expression of CSE1L protein |
decreases expression
|
protein |
11064002
|