PCIDB

KNApSAcK Metabolite C00007496

Metabolite

KNApSAcK Entry

id C00007496
Name Pentachlorophenol
CAS RN 87-86-5
Standard InChI InChI=1S/C6HCl5O/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H
Standard InChI (Main Layer) InChI=1S/C6HCl5O/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H

Cluster

Phytochemical cluster
KCF-S cluster No. 2865

Link

ChEMBL

By standard InChI CHEMBL75967
By standard InChI Main Layer CHEMBL75967

KEGG

By LinkDB C02575

CTD

By CAS RN D010416

Species

Summary

Plant class

class name count

Family

family name count
Sphingomonadaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Sphingobium chlorophenolicum 46429 Sphingomonadaceae Bacteria

Human Protein / Gene in interaction

34 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL75967 CHEMBL2114895 (2)
7 / 44
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL75967 CHEMBL1794499 (1)
2 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL75967 CHEMBL1794524 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL75967 CHEMBL1614544 (1)
11 / 10
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL75967 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL75967 CHEMBL1794399 (1) CHEMBL1794561 (1)
3 / 1
P11473 Vitamin D3 receptor NR1I1 CHEMBL75967 CHEMBL1794311 (2) CHEMBL1794376 (1)
2 / 3
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL75967 CHEMBL1614458 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL75967 CHEMBL1738606 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL75967 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL75967 CHEMBL2114843 (1)
0 / 0
P10145 Interleukin-8 Secreted protein CHEMBL75967 CHEMBL2114835 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL75967 CHEMBL2114788 (1)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL75967 CHEMBL1963863 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL75967 CHEMBL1794467 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL75967 CHEMBL1794382 (2) CHEMBL1794456 (1)
0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL75967 CHEMBL1794510 (2)
5 / 3
Q96RI1 Bile acid receptor NR1H4 CHEMBL75967 CHEMBL1794437 (2)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL75967 CHEMBL1613910 (1) CHEMBL1614227 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL75967 CHEMBL1614038 (1)
2 / 2
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 CHEMBL75967 CHEMBL2114842 (1)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL75967 CHEMBL1794364 (1) CHEMBL1794542 (2)
1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL75967 CHEMBL2114853 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL75967 CHEMBL1737991 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL75967 CHEMBL1614421 (1) CHEMBL1614502 (1)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL75967 CHEMBL1738184 (1) CHEMBL2114890 (2)
0 / 0
P10275 Androgen receptor NR3C4 CHEMBL75967 CHEMBL1794321 (1) CHEMBL1794560 (1)
3 / 4
P35869 Aryl hydrocarbon receptor Transcription Factor CHEMBL75967 CHEMBL2114849 (2)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL75967 CHEMBL1794536 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL75967 CHEMBL2354311 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL75967 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL75967 CHEMBL1614257 (1)
1 / 3
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL75967 CHEMBL2114738 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL75967 CHEMBL2354287 (1)
1 / 1

CTD interaction (41)

compound gene gene name gene description interaction interaction type form reference
pmid
D010416 126 ADH1C
ADH3
alcohol dehydrogenase 1C (class I), gamma polypeptide (EC:1.1.1.1) Pentachlorophenol inhibits the reaction [ADH1C protein results in increased metabolism of Ethanol] decreases reaction
/ increases metabolic processing
protein 19822198
D010416 127 ADH4
ADH-2
alcohol dehydrogenase 4 (class II), pi polypeptide (EC:1.1.1.1) Pentachlorophenol inhibits the reaction [ADH4 protein results in increased metabolism of Ethanol] decreases reaction
/ increases metabolic processing
protein 19822198
D010416 128 ADH5
ADH-3
ADHX
FALDH
FDH
GSH-FDH
GSNOR
alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) Pentachlorophenol inhibits the reaction [ADH5 protein results in increased metabolism of 1-Octanol] decreases reaction
/ increases metabolic processing
protein 19822198
D010416 131 ADH7
ADH4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (EC:1.1.1.1) Pentachlorophenol inhibits the reaction [ADH7 protein results in increased metabolism of Ethanol] decreases reaction
/ increases metabolic processing
protein 19822198
D010416 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Pentachlorophenol results in decreased activity of CASP3 protein decreases activity
protein 19766705
D010416 6348 CCL3
G0S19-1
LD78ALPHA
MIP-1-alpha
MIP1A
SCYA3
chemokine (C-C motif) ligand 3 Pentachlorophenol results in increased expression of CCL3 mRNA increases expression
mRNA 18486366
D010416 1234 CCR5
CC-CKR-5
CCCKR5
CCR-5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
chemokine (C-C motif) receptor 5 (gene/pseudogene) Pentachlorophenol results in decreased expression of CCR5 mRNA decreases expression
mRNA 18486366
D010416 1434 CSE1L
CAS
CSE1
XPO2
CSE1 chromosome segregation 1-like (yeast) Pentachlorophenol results in decreased expression of CSE1L protein decreases expression
protein 11064002
D010416 1583 CYP11A1
CYP11A
CYPXIA1
P450SCC
cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) Pentachlorophenol results in decreased expression of CYP11A1 mRNA decreases expression
mRNA 21296122
D010416 1586 CYP17A1
CPT7
CYP17
P450C17
S17AH
cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) Pentachlorophenol results in decreased expression of CYP17A1 mRNA decreases expression
mRNA 21296122
D010416 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Pentachlorophenol results in decreased expression of CYP19A1 mRNA decreases expression
mRNA 21296122
D010416 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Pentachlorophenol results in increased activity of CYP1A1 protein increases activity
protein 8812189
D010416 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Pentachlorophenol results in increased expression of CYP1A1 protein increases expression
protein 12724925
D010416 1555 CYP2B6
CPB6
CYP2B
CYP2B7
CYP2B7P
CYPIIB6
EFVM
IIB1
P450
cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) Pentachlorophenol results in increased expression of CYP2B6 protein increases expression
protein 15548381
D010416 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) CYP2E1 protein results in increased oxidation of Pentachlorophenol increases oxidation
protein 7747284
D010416 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Pentachlorophenol results in increased expression of CYP3A4 protein increases expression
protein 15548381
D010416 1551 CYP3A7
CP37
CYPIIIA7
P450-HFLA
cytochrome P450, family 3, subfamily A, polypeptide 7 (EC:1.14.14.1) Pentachlorophenol results in increased expression of CYP3A7 protein increases expression
protein 8812189
D010416 11080 DNAJB4
DNAJW
DjB4
HLJ1
DnaJ (Hsp40) homolog, subfamily B, member 4 Pentachlorophenol results in increased expression of DNAJB4 mRNA increases expression
mRNA 18486366
D010416 2071 ERCC3
BTF2
GTF2H
RAD25
TFIIH
XPB
excision repair cross-complementing rodent repair deficiency, complementation group 3 (EC:3.6.4.12) Pentachlorophenol results in increased expression of ERCC3 mRNA increases expression
mRNA 18486366
D010416 2072 ERCC4
ERCC11
FANCQ
RAD1
XPF
excision repair cross-complementing rodent repair deficiency, complementation group 4 Pentachlorophenol results in increased expression of ERCC4 mRNA increases expression
mRNA 18486366
D010416 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Pentachlorophenol binds to and results in decreased activity of ESR1 protein affects binding
/ decreases activity
protein 16626760
D010416 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Pentachlorophenol binds to ESR1 protein affects binding
protein 15081572
D010416 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Pentachlorophenol inhibits the reaction [Estradiol binds to ESR1 protein] affects binding
/ decreases reaction
protein 15081572
D010416 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Pentachlorophenol affects the expression of FOS protein affects expression
protein 12724925
D010416 3295 HSD17B4
DBP
MFE-2
MPF-2
PRLTS1
SDR8C1
hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12) Pentachlorophenol results in decreased expression of HSD17B4 mRNA decreases expression
mRNA 21296122
D010416 3283 HSD3B1
3BETAHSD
HSD3B
HSDB3
HSDB3A
I
SDR11E1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) Pentachlorophenol results in decreased expression of HSD3B1 mRNA decreases expression
mRNA 21296122
D010416 3320 HSP90AA1
EL52
HSP86
HSP89A
HSP90A
HSP90N
HSPC1
HSPCA
HSPCAL1
HSPCAL4
HSPN
Hsp89
Hsp90
LAP2
heat shock protein 90kDa alpha (cytosolic), class A member 1 Pentachlorophenol results in increased expression of HSP90AA1 mRNA increases expression
mRNA 18486366
D010416 59067 IL21
IL-21
Za11
interleukin 21 Pentachlorophenol results in increased expression of IL21 mRNA increases expression
mRNA 18486366
D010416 4055 LTBR
CD18
D12S370
LT-BETA-R
TNF-R-III
TNFCR
TNFR-RP
TNFR2-RP
TNFR3
TNFRSF3
lymphotoxin beta receptor (TNFR superfamily, member 3) Pentachlorophenol results in increased expression of LTBR mRNA increases expression
mRNA 18486366
D010416 9 NAT1
AAC1
MNAT
NAT-1
NATI
N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) Pentachlorophenol inhibits the reaction [NAT1 protein results in increased acetylation of 4-Aminobenzoic Acid] decreases reaction
/ increases acetylation
protein 11470991
D010416 5241 PGR
NR3C3
PR
progesterone receptor Pentachlorophenol results in decreased activity of PGR protein decreases activity
protein 17304841
D010416 5447 POR
CPR
CYPOR
P450R
P450 (cytochrome) oxidoreductase (EC:1.6.2.4) Pentachlorophenol results in increased expression of POR mRNA increases expression
mRNA 18486366
D010416 5886 RAD23A
HHR23A
HR23A
RAD23 homolog A (S. cerevisiae) Pentachlorophenol results in increased expression of RAD23A mRNA increases expression
mRNA 18486366
D010416 6462 SHBG
ABP
SBP
TEBG
sex hormone-binding globulin Pentachlorophenol inhibits the reaction [Dihydrotestosterone binds to SHBG protein] affects binding
/ decreases reaction
protein 9171990
D010416 6770 STAR
STARD1
steroidogenic acute regulatory protein Pentachlorophenol results in decreased expression of STAR mRNA decreases expression
mRNA 21296122
D010416 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Pentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein] affects cotreatment
/ decreases reaction
/ increases activity
protein 16601080
D010416 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Pentachlorophenol affects the expression of TP53 protein affects expression
protein 12724925
D010416 8717 TRADD
Hs.89862
TNFRSF1A-associated via death domain Pentachlorophenol results in increased expression of TRADD mRNA increases expression
mRNA 18486366
D010416 54575 UGT1A10
UDPGT
UGT-1J
UGT1-10
UGT1.10
UGT1J
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) Pentachlorophenol results in increased expression of UGT1A10 mRNA increases expression
mRNA 18486366
D010416 6846 XCL2
SCM-1b
SCM1B
SCYC2
chemokine (C motif) ligand 2 Pentachlorophenol results in decreased expression of XCL2 mRNA decreases expression
mRNA 18486366
D010416 7518 XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4 Pentachlorophenol results in increased expression of XRCC4 mRNA increases expression
mRNA 18486366

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (52)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
%606641 Body mass index; bmi P37231
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#119900 Digital clubbing, isolated congenital P15428
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (73)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

23 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D002759 D010416 Adenoma, Bile Duct marker/mechanism
12597444
D018248 D010416 Adenoma, Liver Cell marker/mechanism
1987363
D000310 D010416 Adrenal Gland Neoplasms marker/mechanism
10696769
D002653 D010416 Child Behavior Disorders marker/mechanism
20049217
D018281 D010416 Cholangiocarcinoma marker/mechanism
12597444
D003072 D010416 Cognition Disorders marker/mechanism
20049217
D056486 D010416 Drug-Induced Liver Injury marker/mechanism
22331495
D006394 D010416 Hemangiosarcoma marker/mechanism
15200160
D006529 D010416 Hepatomegaly marker/mechanism
20654147
D006965 D010416 Hyperplasia marker/mechanism
20654147
D015470 D010416 Leukemia, Myeloid, Acute marker/mechanism
1987363
D008113 D010416 Liver Neoplasms marker/mechanism
10696769
D008223 D010416 Lymphoma marker/mechanism
12669308
D008659 D010416 Metabolic Diseases marker/mechanism
20064833
D019957 D010416 Motor Skills Disorders marker/mechanism
20049217
D018777 D010416 Multiple Chemical Sensitivity marker/mechanism
8766847
D018301 D010416 Neoplasms, Mesothelial marker/mechanism
10696769
D009422 D010416 Nervous System Diseases marker/mechanism
8766847
D009845 D010416 Oligospermia marker/mechanism
10434936
D011041 D010416 Poisoning marker/mechanism
8766847
D011297 D010416 Prenatal Exposure Delayed Effects marker/mechanism
20049217
D013160 D010416 Splenic Neoplasms marker/mechanism
10696769
D013959 D010416 Thyroid Diseases marker/mechanism
20654147