PCIDB

KNApSAcK Metabolite C00008145

Metabolite

KNApSAcK Entry

id C00008145
Name Pinocembrin 5,7-dimethyl ether
CAS RN 36052-66-1
Standard InChI InChI=1S/C17H16O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-9,14H,10H2,1-2H3
Standard InChI (Main Layer) InChI=1S/C17H16O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-9,14H,10H2,1-2H3

Cluster

Phytochemical cluster No. 14
KCF-S cluster No. 25

Link

ChEMBL

By standard InChI CHEMBL107131
By standard InChI Main Layer CHEMBL107131 CHEMBL1253912

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
Magnoliophyta 1
rosids 1

Family

family name count
Lauraceae 1
Myrtaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aniba riparia 128591 Lauraceae Magnoliophyta Viridiplantae
Eucalyptus sieberi 87684 Myrtaceae rosids Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL107131 CHEMBL1794499 (1)
2 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL107131 CHEMBL1614458 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL107131 CHEMBL1613808 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL107131 CHEMBL1613910 (1)
3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL107131 CHEMBL1687393 (1) CHEMBL1687394 (1)
2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL107131 CHEMBL1614038 (1)
2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL107131 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
O14746 Telomerase reverse transcriptase Enzyme CHEMBL1253912 CHEMBL1251398 (1)
5 / 5
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL107131 CHEMBL1613914 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609135 Aplastic anemia O14746
#614490 Blood group, junior system; jr Q9UNQ0
#119900 Digital clubbing, isolated congenital P15428
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (11)

KEGG disease name UniProt
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
H00024 Prostate cancer O14746 (marker)
H00036 Osteosarcoma P08684 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)