PCIDB

KNApSAcK Metabolite C00008281

Metabolite

KNApSAcK Entry

id C00008281
Name Isookanin
CAS RN 489-73-6
Standard InChI InChI=1S/C15H12O6/c16-9-3-1-7(5-12(9)19)13-6-11(18)8-2-4-10(17)14(20)15(8)21-13/h1-5,13,16-17,19-20H,6H2
Standard InChI (Main Layer) InChI=1S/C15H12O6/c16-9-3-1-7(5-12(9)19)13-6-11(18)8-2-4-10(17)14(20)15(8)21-13/h1-5,13,16-17,19-20H,6H2

Cluster

Phytochemical cluster No. 14
KCF-S cluster No. 25

Link

ChEMBL

By standard InChI CHEMBL1505816
By standard InChI Main Layer CHEMBL1505816

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Fabaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia spp. 3808 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

22 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein CHEMBL1505816 CHEMBL1614529 (1)
0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1505816 CHEMBL1738312 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL1505816 CHEMBL1614079 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL1505816 CHEMBL1614076 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1505816 CHEMBL1794585 (1)
0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily CHEMBL1505816 CHEMBL1614153 (1)
1 / 4
P54132 Bloom syndrome protein Enzyme CHEMBL1505816 CHEMBL1614067 (1)
1 / 2
P39748 Flap endonuclease 1 Enzyme CHEMBL1505816 CHEMBL1794486 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL1505816 CHEMBL2114780 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1505816 CHEMBL1794569 (1)
1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL1505816 CHEMBL1738679 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL1505816 CHEMBL1738602 (1)
3 / 1
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1505816 CHEMBL1794401 (1)
0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL1505816 CHEMBL1738040 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1505816 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1505816 CHEMBL1737991 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL1505816 CHEMBL1614211 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1505816 CHEMBL1614250 (1) CHEMBL1614421 (1)
CHEMBL1614502 (1)
4 / 3
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1505816 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL1505816 CHEMBL1613914 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL1505816 CHEMBL1613829 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1505816 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#208900 Ataxia-telangiectasia; at Q13315
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG disease name UniProt
H00213 Hypophosphatasia P05186 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)