KCF-S cluster No. 1028 (9 metabolites)

Corresponding Phytochemical cluster No. 4

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	11
asterids	8

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Cumulative family count

class name	count
Calycanthaceae	11
Rubiaceae	8

KEGG BRITE br08003

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Categories (3)

br08003 Category	# of metabolite
Indole alkaloids	1
Pyrroloindole alkaloids	1
Others	1

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Indole alkaloids	C09097	C00001700
Pyrroloindole alkaloids	C09133	C00001708
Others	C10573	C00002318

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001700	Calycanthidine
C00001708	Chimonanthin / (-)-Chimonanthine	CHEMBL464977 CHEMBL1895573		3 / 0 / 0
C00002318	Calycanthine / (+)-Calycanthine	CHEMBL464770 CHEMBL1733079 CHEMBL1981354	C070236	9 / 2 / 3
C00026555	(+)-Chimonanthine	CHEMBL464977 CHEMBL1895573		3 / 0 / 0
C00026644	Chimonanthidine / (-)-Chimonanthidine
C00026840	meso-Chimonanthine	CHEMBL464977 CHEMBL1895573		3 / 0 / 0
C00049661	Nb-Desmethyl-meso-chimonanthine / (+)-Nb-Desmethyl-meso-chimonanthine
C00049765	(-)-Calycanthine	CHEMBL464770 CHEMBL1733079 CHEMBL1981354		9 / 2 / 3
C00049794	Isocalycanthine

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001708 C00002318 C00026555 C00026840 C00049765	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001708 C00026555 C00026840	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001708 C00026555 C00026840	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002318 C00049765	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002318 C00049765	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002318 C00049765	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002318 C00049765	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002318 C00049765	0 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002318 C00049765	0 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002318 C00049765	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002318 C00049765	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions