| class name | count |
|---|
| class name | count |
|---|---|
| Streptomycetaceae | 9 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00014920
|
K 99-5278A
/ Takanawaene A / Fungicide K 99-5278A |
|
||||
|
C00014921
|
K 99-5278B
/ Takanawaene B / Fungicide K 99-5278B |
|
||||
|
C00014922
|
K 99-5278C
/ Takanawaene C / Fungicide K 99-5278C |
|
||||
|
C00016899
|
RK 397
|
CHEMBL2007106
|
|
|||
|
C00017672
|
Isochainin
|
|
||||
|
C00018790
|
Filipin II
|
|
||||
|
C00018791
|
Filipin III
|
CHEMBL154669
CHEMBL1562334 CHEMBL1981819 CHEMBL2103755 |
D005372
|
5 / 5 / 4 | 6 / 1 |
|
|
C00018792
|
Filipin IV
|
CHEMBL154669
CHEMBL1562334 CHEMBL1981819 CHEMBL2103755 |
5 / 5 / 4 |
|
||
|
C00018805
|
Cantricin
/ Cogomycin / Pentamycin / NSC 276732 / NSC 105388 / Fungichromin / Antibiotic A 246 / Lagosin (antibiotic) |
CHEMBL1882386
CHEMBL1993028 |
C011827
|
2 / 0 / 0 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00018791 C00018792 | 3 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00018791 C00018792 | 1 / 1 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00018791 C00018792 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00018791 C00018792 | 1 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00018791 C00018792 | 0 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00018805 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00018805 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00018791
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00018791
|
| 3716 | JAK1, JAK1A, JAK1B, JTK3 | Janus kinase 1 (EC:2.7.10.2) |
C00018791
|
| 5621 | PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30 | prion protein |
C00018791
|
| 6714 | SRC, ASV, SRC1, c-SRC, p60-Src | v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2) |
C00018791
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00018791
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #607276 | Resting heart rate, variation in |
P08588
|