KCF-S cluster No. 123 (41 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (41)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	64

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Cumulative family count

class name	count
Clusiaceae	59
Hypericaceae	3
Calophyllaceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (41)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002991	Garcinol	CHEMBL454261 CHEMBL502489 CHEMBL2087609	C054597	2 / 1 / 1	17 / 0
C00003023	Xanthochymol	CHEMBL454261 CHEMBL502489 CHEMBL2087609	C414432	2 / 1 / 1
C00031902	Cambogin / Isogarcinol	CHEMBL458934 CHEMBL1077027 CHEMBL1098255 CHEMBL2087611		2 / 1 / 1
C00033898	Guttiferone E	CHEMBL454261 CHEMBL502489 CHEMBL2087609		2 / 1 / 1
C00035255	Camboginol / (-)-Camboginol
C00035323	Guttiferone I
C00036893	Chamone I
C00036894	Chamone II
C00037230	Guttiferone F / (-)-Guttiferone F	CHEMBL454261 CHEMBL502489 CHEMBL2087609		2 / 1 / 1
C00037540	Nemorosone II	CHEMBL583445 CHEMBL2088617
C00038318	7-Epiclusianone	CHEMBL459015 CHEMBL1629877
C00039302	Guttiferone L / (-)-Guttiferone L	CHEMBL387644
C00039303	Guttiferone K	CHEMBL388529 CHEMBL452483 CHEMBL1629876		2 / 0 / 1
C00041705	Oblongifolin A / (+)-Oblongifolin A	CHEMBL449424 CHEMBL505370
C00041706	Oblongifolin B / (+)-Oblongifolin B	CHEMBL449424 CHEMBL505370
C00041707	Oblongifolin C / (+)-Oblongifolin C	CHEMBL443681 CHEMBL445689		2 / 0 / 0
C00041708	Oblongifolin D / (+)-Oblongifolin D	CHEMBL509795 CHEMBL442991
C00042241	Aristophenone A	CHEMBL516196
C00042436	Cycloxanthochymol	CHEMBL1098252 CHEMBL1098256
C00042537	Garcinielliptone FB	CHEMBL404741
C00042570	Guttiferone H / (+)-Guttiferone H	CHEMBL444720
C00042642	Isoxanthochymol / (+)-Isoxanthochymol	CHEMBL458934 CHEMBL1077027 CHEMBL1098255 CHEMBL2087611		2 / 1 / 1
C00043589	Hyperibone L	CHEMBL485062
C00044628	Clusianone	CHEMBL459015 CHEMBL1629877
C00044780	Garcinol 13-O-methyl ether / (-)-Garcinol 13-O-methyl ether	CHEMBL505686
C00044823	Isogarcinol 13-O-methyl ether	CHEMBL502089
C00047134	13,14-Didehydroxyisogarcinol / (-)-13,14-Didehydroxyisogarcinol	CHEMBL554161
C00047135	13-Hydroxygarcimultiflorone B / (-)-13-Hydroxygarcimultiflorone B	CHEMBL555031
C00047239	Garcimultiflorone B / (-)-Garcimultiflorone B	CHEMBL556137
C00047242	Guttiferone B / (-)-Guttiferone B	CHEMBL509795 CHEMBL442991
C00048298	7-epi-Garcinol	CHEMBL454261 CHEMBL502489 CHEMBL2087609		2 / 1 / 1
C00048299	7-epi-Isogarcinol	CHEMBL458934 CHEMBL1077027 CHEMBL1098255 CHEMBL2087611		2 / 1 / 1
C00048353	Coccinone A / (+)-Coccinone A	CHEMBL1253757
C00048354	Coccinone B / (-)-Coccinone B
C00048355	Coccinone C / (-)-Coccinone C
C00048356	Coccinone D / (-)-Coccinone D
C00048357	Coccinone E / (-)-Coccinone E
C00048358	Coccinone F / (-)-Coccinone F
C00048359	Coccinone G / (-)-Coccinone G
C00048360	Coccinone H / (+)-Coccinone H
C00049464	Laxifloranone / (+)-Laxifloranone	CHEMBL522850

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q09472	Histone acetyltransferase p300	Enzyme	C00002991 C00003023 C00031902 C00033898 C00037230 C00042642 C00048298 C00048299	1 / 1
Q92831	Histone acetyltransferase KAT2B	Enzyme	C00002991 C00003023 C00031902 C00033898 C00037230 C00042642 C00048298 C00048299	0 / 0
P08311	Cathepsin G	S1A	C00039303	0 / 0
P07858	Cathepsin B	C1A	C00039303	0 / 1
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00041707	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00041707	0 / 0

17 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002991
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002991
637	BID, FP497	BH3 interacting domain death agonist	C00002991
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002991
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002991
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002991
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00002991
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002991
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002991
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002991
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002991
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002991
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00002991
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00002991
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002991
6714	SRC, ASV, SRC1, c-SRC, p60-Src	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2)	C00002991
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002991

Related Diseases

Diseases related to proteins in ChEMBL interactions