KCF-S cluster No. 1304 (7 metabolites)

Corresponding Phytochemical cluster No. 35

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
Spermatophyta	21

---

Cumulative family count

class name	count
Cupressaceae	21

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Cyclic monoterpenes	2

---

metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Cyclic monoterpenes	C09904	C00003062
Cyclic monoterpenes	C09905	C00003063

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003062	beta-Thujaplicin	CHEMBL48310	C009479	27 / 27 / 50
C00003063	gamma-Thujaplicin	CHEMBL1275999
C00011000	2,7-Dihydroxy-3-isopropyl-2,4,6-cycloheptatrienone
C00011001	Pygmaein
C00011002	Isopygmaein
C00011011	alpha-Thujaplicin / 2-Hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one	CHEMBL1275969
C00011012	Nezukone / 4-Isopropyl-2,4,6-cycloheptatrien-1-one

Human Protein / Gene in interactions

27 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04637	Cellular tumor antigen p53	Transcription Factor	C00003062	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00003062	4 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00003062	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00003062	0 / 0
P22894	Neutrophil collagenase	M10A	C00003062	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00003062	2 / 2
P11473	Vitamin D3 receptor	NR1I1	C00003062	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00003062	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00003062	0 / 0
P42858	Huntingtin	Unclassified protein	C00003062	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003062	0 / 0
P03956	Interstitial collagenase	M10A	C00003062	0 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00003062	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00003062	2 / 0
P08253	72 kDa type IV collagenase	M10A	C00003062	1 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00003062	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003062	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003062	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003062	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00003062	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003062	0 / 0
P08254	Stromelysin-1	M10A	C00003062	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00003062	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003062	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003062	1 / 1
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003062	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00003062	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions