| class name | count |
|---|---|
| Spermatophyta | 13 |
| class name | count |
|---|---|
| Cephalotaxaceae | 13 |
| br08003 Category | # of metabolite |
|---|---|
| Isoquinoline alkaloids | 1 |
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Isoquinoline alkaloids | C10580 | C00002324 |
| Isoquinoline alkaloids | C10580 | C00027319 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00002324
|
Cephalotaxine
|
CHEMBL276462
CHEMBL1476895 |
C001597
|
4 / 7 / 7 |
|
|
|
C00025585
|
Epicephalotaxine
|
CHEMBL276462
CHEMBL1476895 |
4 / 7 / 7 |
|
||
|
C00025586
|
Cephalotaxinone
|
|
||||
|
C00027247
|
11-Hydroxycephalotaxine
/ 11alpha-Hydroxycephalotaxine |
C007992
|
|
|||
|
C00027319
|
Cephalotaxine
/ (-)-Cephalotaxine |
CHEMBL276462
CHEMBL1476895 |
C001597
|
4 / 7 / 7 |
|
|
|
C00028395
|
Isocephalotaxine
|
CHEMBL517319
|
|
|||
|
C00044621
|
Cephalotaxine beta-N-oxide
|
CHEMBL517318
CHEMBL464200 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002324 C00025585 C00027319 | 3 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002324 C00025585 C00027319 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002324 C00025585 C00027319 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002324 C00025585 C00027319 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|