KCF-S cluster No. 1566 (6 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| eudicotyledons | 17 |
| Euphyllophyta | 1 |
Cumulative family count
| class name | count |
|---|---|
| Paeoniaceae | 17 |
| Salviniaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00003011
|
Paeoniflorin
|
CHEMBL1078549
CHEMBL1397567 CHEMBL1972762 |
C015423
|
4 / 4 / 8 | 3 / 2 |
|
|
C00011060
|
Lactiflorin
|
|
||||
|
C00032108
|
Paeonin B
/ (+)-Paeonin B |
CHEMBL1078549
CHEMBL1397567 CHEMBL1972762 |
4 / 4 / 8 |
|
||
|
C00033281
|
Oxypaeoniflorin
|
CHEMBL1078550
|
C047593
|
|
||
|
C00033623
|
Albiflorin
|
CHEMBL1939883
|
C014959
|
1 / 1 / 1 |
|
|
|
C00048043
|
Paeonin C
/ (+)-Paeonin C |
CHEMBL1078550
|
|
Human Protein / Gene in interactions
4 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P03372 | Estrogen receptor | NR3A1 | C00003011 C00032108 C00033623 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003011 C00032108 | 2 / 5 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003011 C00032108 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003011 C00032108 | 1 / 2 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00003011
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00003011
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003011
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|