PCIDB

KCF-S cluster No. 1829 (6 metabolites)

Plant Species

Cumulative plant class count

class name count
rosids 4
asterids 3

Cumulative family count

class name count
Rosaceae 3
Apiaceae 2
Asteraceae 1
Salicaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00002766 External link 512 Phenetyl caffeate
CHEMBL319244
CHEMBL1397711
C055494
139 / 92 / 90 37 / 20
C00022586 External link 512 2-Phenylethyl ferulate
CHEMBL442022
C00032180 External link 512 Spiraformin A
C00032181 External link 512 Spiraformin B
C00032182 External link 512 Spiraformin C
C00041758 External link 512 p-Hydroxyphenethyl trans-ferulate
/ p-Hydroxyphenylethyl-trans-ferulate
CHEMBL481245
1 / 0 / 0

Human Protein / Gene in interactions

140 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002766 1 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00002766 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002766 7 / 37
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00002766 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00002766 4 / 1
Q99700 Ataxin-2 Unclassified protein C00002766 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00002766 2 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002766 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00002766 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00002766 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002766 0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002766 2 / 2
P08246 Neutrophil elastase S1A C00002766 2 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00002766 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00002766 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002766 0 / 0
P29466 Caspase-1 C14 C00002766 0 / 0
P17252 Protein kinase C alpha type Alpha C00002766 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00002766 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002766 2 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002766 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002766 11 / 10
P37840 Alpha-synuclein Unclassified protein C00002766 4 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00002766 3 / 2
P00918 Carbonic anhydrase 2 Lyase C00002766 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002766 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002766 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00002766 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00002766 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00002766 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002766 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002766 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002766 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00041758 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002766 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002766 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002766 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002766 0 / 1
P54132 Bloom syndrome protein Enzyme C00002766 1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002766 1 / 8
P14416 D(2) dopamine receptor Dopamine receptor C00002766 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002766 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002766 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002766 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002766 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00002766 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002766 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002766 1 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00002766 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002766 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002766 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002766 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002766 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00002766 0 / 0
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00002766 0 / 0
O75496 Geminin Unclassified protein C00002766 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002766 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002766 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002766 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002766 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002766 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002766 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002766 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002766 0 / 0
P15121 Aldose reductase Enzyme C00002766 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00002766 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002766 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002766 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002766 0 / 0
P08311 Cathepsin G S1A C00002766 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002766 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002766 0 / 0
P03956 Interstitial collagenase M10A C00002766 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002766 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00002766 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002766 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00002766 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002766 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002766 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002766 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002766 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002766 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002766 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002766 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002766 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00002766 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002766 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002766 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002766 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00002766 2 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002766 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002766 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002766 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002766 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002766 3 / 3
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00002766 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002766 2 / 2
Q01453 Peripheral myelin protein 22 Unclassified protein C00002766 5 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002766 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002766 0 / 0
P03372 Estrogen receptor NR3A1 C00002766 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002766 1 / 0
P22303 Acetylcholinesterase Hydrolase C00002766 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002766 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002766 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002766 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002766 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00002766 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002766 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002766 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00002766 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002766 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002766 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002766 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002766 0 / 0
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00002766 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002766 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002766 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002766 4 / 3
Q99549 M-phase phosphoprotein 8 Unclassified protein C00002766 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002766 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002766 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002766 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002766 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002766 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002766 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00002766 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002766 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002766 0 / 0
P40225 Thrombopoietin Unclassified protein C00002766 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002766 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002766 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002766 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00002766 0 / 0
O00255 Menin Unclassified protein C00002766 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002766 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00002766 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002766 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002766 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002766 1 / 1

37 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00002766
196 AHR, bHLHe76 aryl hydrocarbon receptor C00002766
9564 BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas breast cancer anti-estrogen resistance 1 C00002766
329 BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 baculoviral IAP repeat containing 2 C00002766
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00002766
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00002766
891 CCNB1, CCNB cyclin B1 C00002766
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00002766
898 CCNE1, CCNE cyclin E1 C00002766
929 CD14 CD14 molecule C00002766
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00002766
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00002766
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00002766
1053 CEBPE, C/EBP-epsilon, CRP1 CCAAT/enhancer binding protein (C/EBP), epsilon C00002766
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00002766
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00002766
3458 IFNG, IFG, IFI interferon, gamma C00002766
3606 IL18, IGIF, IL-18, IL-1g, IL1F4 interleukin 18 (interferon-gamma-inducing factor) C00002766
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002766
3558 IL2, IL-2, TCGF, lymphokine interleukin 2 C00002766
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002766
3684 ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6 integrin, alpha M (complement component 3 receptor 3 subunit) C00002766
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002766
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00002766
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00002766
4791 NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) C00002766
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00002766
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00002766
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002766
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002766
6196 RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3 ribosomal protein S6 kinase, 90kDa, polypeptide 2 (EC:2.7.11.1) C00002766
7042 TGFB2, LDS4, TGF-beta2 transforming growth factor, beta 2 C00002766
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00002766
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00002766
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00002766
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00002766
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00002766

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (92)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103780 Alcohol dependence P08172
P14416
P31645
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P18054
#162800 Cyclic neutropenia P08246
#127750 Dementia, lewy body; dlb P37840
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#603932 Intervertebral disc disease; idd P14780
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (90)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

20 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002286 Carcinoma, Ehrlich Tumor C00002766
D005910 Glioma C00002766
D006331 Heart Diseases C00002766
D020925 Hypoxia-Ischemia, Brain C00002766
D007414 Intestinal Neoplasms C00002766
D007674 Kidney Diseases C00002766
D015473 Leukemia, Promyelocytic, Acute C00002766
D008107 Liver Diseases C00002766
D008113 Liver Neoplasms C00002766
D008545 Melanoma C00002766
D028361 Mitochondrial Diseases C00002766
D009203 Myocardial Infarction C00002766
D009336 Necrosis C00002766
D009361 Neoplasm Invasiveness C00002766
D009362 Neoplasm Metastasis C00002766
D009410 Nerve Degeneration C00002766
D011041 Poisoning C00002766
D011230 Precancerous Conditions C00002766
D015427 Reperfusion Injury C00002766
D013118 Spinal Cord Diseases C00002766