KCF-S cluster No. 2144 (5 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 6 |
Cumulative family count
| class name | count |
|---|---|
| Apocynaceae | 6 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001710
|
Cryptolepine
|
CHEMBL119096
CHEMBL456244 |
C024015
|
24 / 0 |
|
|
|
C00026782
|
Isocryptolepine
/ Cryptosanguinolentine |
CHEMBL596333
|
|
|||
|
C00026816
|
Cryptosanguinolentine
|
CHEMBL596333
|
|
|||
|
C00026906
|
11-Isopropylcryptolepine
|
CHEMBL172137
CHEMBL1181479 |
|
|||
|
C00050266
|
11-Hydroxycryptolepine
|
CHEMBL504189
|
|
Human Protein / Gene in interactions
24 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001710
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00001710
|
| 699 | BUB1, BUB1A, BUB1L, hBUB1 | BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) |
C00001710
|
| 701 | BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1 | BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1) |
C00001710
|
| 890 | CCNA2, CCN1, CCNA | cyclin A2 |
C00001710
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00001710
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00001710
|
| 995 | CDC25C, CDC25, PPP1R60 | cell division cycle 25C (EC:3.1.3.48) |
C00001710
|
| 997 | CDC34, E2-CDC34, UBC3, UBCH3, UBE2R1 | cell division cycle 34 (EC:6.3.2.19) |
C00001710
|
| 31052 |
C00001710
|
||
| 990 | CDC6, CDC18L, HsCDC18, HsCDC6 | cell division cycle 6 |
C00001710
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001710
|
| 1033 | CDKN3, CDI1, CIP2, KAP, KAP1 | cyclin-dependent kinase inhibitor 3 (EC:3.1.3.16 3.1.3.48) |
C00001710
|
| 1063 | CENPF, CENF, PRO1779, hcp-1 | centromere protein F, 350/400kDa |
C00001710
|
| 9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00001710
|
| 4171 | MCM2, BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19 | minichromosome maintenance complex component 2 (EC:3.6.4.12) |
C00001710
|
| 4175 | MCM6, MCG40308, Mis5, P105MCM | minichromosome maintenance complex component 6 (EC:3.6.4.12) |
C00001710
|
| 4176 | MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146 | minichromosome maintenance complex component 7 (EC:3.6.4.12) |
C00001710
|
| 84515 | MCM8, C20orf154, dJ967N21.5 | minichromosome maintenance complex component 8 (EC:3.6.4.12) |
C00001710
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00001710
|
| 4661 | MYT1, C20orf36, MTF1, MYTI, PLPB1, ZC2HC4A | myelin transcription factor 1 |
C00001710
|
| 4751 | NEK2, HsPK21, NEK2A, NLK1 | NIMA-related kinase 2 (EC:2.7.11.1) |
C00001710
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001710
|
| 7272 | TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT | TTK protein kinase (EC:2.7.12.1) |
C00001710
|