KCF-S cluster No. 2164 (5 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	9

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Cumulative family count

class name	count
Zingiberaceae	9

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00032769	bis-Demethoxycurcumin / bis-(4-hydroxycinnamoyl)methane / p,p'-Dihydroxydicinnamoyl methane	CHEMBL105350	C034786	4 / 2 / 3	18 / 4
C00033297	Monodemethoxycurcumin / p-Hydroxycinnamoyl feruloyl methane		C050229		17 / 3
C00033502	(1E,6E)-1,7-Diphenyl-1,6-heptadiene-3,5-dione	CHEMBL102914
C00037023	Curcumin II / Demethoxycurcumin
C00042286	Bisdemethoxycurcumin	CHEMBL105350	C475935	4 / 2 / 3	1 / 0

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00032769 C00042286	0 / 3
Q9UQM7	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Camk2	C00032769 C00042286	0 / 0
P26358	DNA (cytosine-5)-methyltransferase 1	Transferase	C00032769 C00042286	2 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00032769 C00042286	0 / 0

22 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00032769 C00033297 C00042286
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00032769 C00033297
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00032769 C00033297
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00032769 C00033297
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00032769 C00033297
7490	WT1, AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33	Wilms tumor 1	C00032769 C00033297
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00032769 C00033297
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00032769 C00033297
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00032769 C00033297
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00032769 C00033297
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00032769 C00033297
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00032769 C00033297
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00032769 C00033297
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00032769
7098	TLR3, CD283, IIAE2	toll-like receptor 3	C00032769
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00032769
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00032769
4248	MGAT3, GNT-III, GNT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (EC:2.4.1.144)	C00032769
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00033297
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00033297
3791	KDR, CD309, FLK1, VEGFR, VEGFR2	kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1)	C00033297
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00033297

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions