Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Didymellaceae 2

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00015456 External link 512 L 783277
CHEMBL2012519
32 / 51 / 38
C00015457 External link 512 L 783290
CHEMBL2012519
32 / 51 / 38

Human Protein / Gene in interactions

32 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00015456 C00015457 1 / 3
Q16539 Mitogen-activated protein kinase 14 p38 C00015456 C00015457 0 / 0
Q16512 Serine/threonine-protein kinase N1 Pkn C00015456 C00015457 0 / 0
O14965 Aurora kinase A Aur C00015456 C00015457 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00015456 C00015457 0 / 0
P43403 Tyrosine-protein kinase ZAP-70 Syk C00015456 C00015457 1 / 2
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily C00015456 C00015457 0 / 0
Q06187 Tyrosine-protein kinase BTK Tec C00015456 C00015457 2 / 2
Q16513 Serine/threonine-protein kinase N2 Pkn C00015456 C00015457 0 / 0
P23458 Tyrosine-protein kinase JAK1 Jakb C00015456 C00015457 0 / 0
P36507 Dual specificity mitogen-activated protein kinase kinase 2 Ste7 C00015456 C00015457 1 / 1
P29597 Non-receptor tyrosine-protein kinase TYK2 Jakb C00015456 C00015457 1 / 1
P54764 Ephrin type-A receptor 4 Eph C00015456 C00015457 0 / 0
P54760 Ephrin type-B receptor 4 Eph C00015456 C00015457 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00015456 C00015457 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00015456 C00015457 1 / 1
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00015456 C00015457 5 / 4
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00015456 C00015457 5 / 9
O60674 Tyrosine-protein kinase JAK2 Jakb C00015456 C00015457 5 / 1
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00015456 C00015457 1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00015456 C00015457 2 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00015456 C00015457 0 / 0
P22607 Fibroblast growth factor receptor 3 Fgfr C00015456 C00015457 14 / 6
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00015456 C00015457 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00015456 C00015457 0 / 0
Q15118 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial Pdhk C00015456 C00015457 0 / 0
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret C00015456 C00015457 9 / 4
P10721 Mast/stem cell growth factor receptor Kit Pdgfr C00015456 C00015457 4 / 3
P06239 Tyrosine-protein kinase Lck Src C00015456 C00015457 0 / 1
P52333 Tyrosine-protein kinase JAK3 Jakb C00015456 C00015457 1 / 1
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00015456 C00015457 0 / 0
P30530 Tyrosine-protein kinase receptor UFO TK tyrosine-protein kinase AXL subfamily C00015456 C00015457 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (51)

OMIM preferred title UniProt
#100800 Achondroplasia; ach P22607
#300755 Agammaglobulinemia, x-linked; xla Q06187
#109800 Bladder cancer P22607
#600880 Budd-chiari syndrome; bdchs O60674
#610474 Camptodactyly, tall stature, and hearing loss syndrome P22607
#615280 Cardiofaciocutaneous syndrome 4; cfc4 P36507
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#603956 Cervical cancer P22607
#114500 Colorectal cancer; crc P07949
#612247 Crouzon syndrome with acanthosis nigricans; can P22607
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#246200 Donohue syndrome P06213
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#606764 Gastrointestinal stromal tumor; gist P10721
#137800 Glioma susceptibility 1; glm1 P04626
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#146000 Hypochondroplasia; hch P22607
#270450 Insulin-like growth factor i, resistance to P08069
#307200 Isolated growth hormone deficiency, type iii; ighd3 Q06187
#182000 Keratosis, seborrheic P22607
#149730 Lacrimoauriculodentodigital syndrome; ladd P22607
#601626 Leukemia, acute myeloid; aml O60674
P10721
#211980 Lung cancer P04626
#602849 Muenke syndrome; mnkes P22607
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#254450 Myelofibrosis O60674
#254500 Myeloma, multiple P22607
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#162900 Nevus, epidermal P22607
#167000 Ovarian cancer P04626
#171300 Pheochromocytoma P07949
#172800 Piebald trait; pbt P10721
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#263300 Polycythemia vera; pv O60674
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#269840 Selective t-cell defect; stcd P43403
#600802 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative P52333
#273300 Testicular germ cell tumor; tgct P10721
P22607
#187600 Thanatophoric dysplasia, type i; td1 P22607
#187601 Thanatophoric dysplasia, type ii; td2 P22607
#614521 Thrombocythemia 3; thcyt3 O60674
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P07949
#611521 Tyrosine kinase 2 deficiency P29597

KEGG DISEASE (38)

KEGG name UniProt
H00012 Polycythemia vera O60674 (related)
O60674 (marker)
H00018 Gastric cancer P04626 (related)
P08581 (related)
H00019 Pancreatic cancer P04626 (related)
H00022 Bladder cancer P04626 (related)
P22607 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00028 Choriocarcinoma P04626 (related)
H00030 Cervical cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
P43403 (related)
H00032 Thyroid cancer P07949 (related)
P07949 (marker)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00010 Multiple myeloma P22607 (related)
H00458 Craniosynostosis P22607 (related)
H00505 FGFR3-related short limb skeletal dysplasias P22607 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P22607 (related)
H00997 CATSHL syndrome P22607 (related)
H00107 Other well-defined immunodeficiency syndromes P29597 (related)
H00523 Noonan syndrome and related disorders P36507 (related)
H00005 Chronic lymphocytic leukemia (CLL) P43403 (marker)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P52333 (related)
H00085 Agammaglobulinemias Q06187 (related)
H00254 Pituitary Dwarfism (PD) Q06187 (related)
H00014 Non-small cell lung cancer Q9UM73 (related)