class name | count |
---|
class name | count |
---|---|
Didymellaceae | 2 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00015456
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L 783277
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CHEMBL2012519
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32 / 51 / 38 |
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C00015457
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L 783290
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CHEMBL2012519
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32 / 51 / 38 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | C00015456 C00015457 | 1 / 3 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | C00015456 C00015457 | 0 / 0 |
Q16512 | Serine/threonine-protein kinase N1 | Pkn | C00015456 C00015457 | 0 / 0 |
O14965 | Aurora kinase A | Aur | C00015456 C00015457 | 0 / 0 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00015456 C00015457 | 0 / 0 |
P43403 | Tyrosine-protein kinase ZAP-70 | Syk | C00015456 C00015457 | 1 / 2 |
Q9HBH9 | MAP kinase-interacting serine/threonine-protein kinase 2 | CAMK serine/threonine protein kinase MNK subfamily | C00015456 C00015457 | 0 / 0 |
Q06187 | Tyrosine-protein kinase BTK | Tec | C00015456 C00015457 | 2 / 2 |
Q16513 | Serine/threonine-protein kinase N2 | Pkn | C00015456 C00015457 | 0 / 0 |
P23458 | Tyrosine-protein kinase JAK1 | Jakb | C00015456 C00015457 | 0 / 0 |
P36507 | Dual specificity mitogen-activated protein kinase kinase 2 | Ste7 | C00015456 C00015457 | 1 / 1 |
P29597 | Non-receptor tyrosine-protein kinase TYK2 | Jakb | C00015456 C00015457 | 1 / 1 |
P54764 | Ephrin type-A receptor 4 | Eph | C00015456 C00015457 | 0 / 0 |
P54760 | Ephrin type-B receptor 4 | Eph | C00015456 C00015457 | 0 / 0 |
P49841 | Glycogen synthase kinase-3 beta | Gsk | C00015456 C00015457 | 0 / 0 |
Q9UM73 | ALK tyrosine kinase receptor | TKL serine/threonine protein kinase STKR type 1 subfamily | C00015456 C00015457 | 1 / 1 |
P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00015456 C00015457 | 5 / 4 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00015456 C00015457 | 5 / 9 |
O60674 | Tyrosine-protein kinase JAK2 | Jakb | C00015456 C00015457 | 5 / 1 |
P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00015456 C00015457 | 1 / 0 |
P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00015456 C00015457 | 2 / 3 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00015456 C00015457 | 0 / 0 |
P22607 | Fibroblast growth factor receptor 3 | Fgfr | C00015456 C00015457 | 14 / 6 |
Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00015456 C00015457 | 0 / 0 |
O75116 | Rho-associated protein kinase 2 | Rock | C00015456 C00015457 | 0 / 0 |
Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial | Pdhk | C00015456 C00015457 | 0 / 0 |
P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | Ret | C00015456 C00015457 | 9 / 4 |
P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00015456 C00015457 | 4 / 3 |
P06239 | Tyrosine-protein kinase Lck | Src | C00015456 C00015457 | 0 / 1 |
P52333 | Tyrosine-protein kinase JAK3 | Jakb | C00015456 C00015457 | 1 / 1 |
P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00015456 C00015457 | 0 / 0 |
P30530 | Tyrosine-protein kinase receptor UFO | TK tyrosine-protein kinase AXL subfamily | C00015456 C00015457 | 0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#100800 | Achondroplasia; ach |
P22607
|
#300755 | Agammaglobulinemia, x-linked; xla |
Q06187
|
#109800 | Bladder cancer |
P22607
|
#600880 | Budd-chiari syndrome; bdchs |
O60674
|
#610474 | Camptodactyly, tall stature, and hearing loss syndrome |
P22607
|
#615280 | Cardiofaciocutaneous syndrome 4; cfc4 |
P36507
|
#209880 | Central hypoventilation syndrome, congenital; cchs |
P07949
|
#603956 | Cervical cancer |
P22607
|
#114500 | Colorectal cancer; crc |
P07949
|
#612247 | Crouzon syndrome with acanthosis nigricans; can |
P22607
|
#610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
#125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
#246200 | Donohue syndrome |
P06213
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#606764 | Gastrointestinal stromal tumor; gist |
P10721
|
#137800 | Glioma susceptibility 1; glm1 |
P04626
|
#602089 | Hemangioma, capillary infantile |
P35968
|
#114550 | Hepatocellular carcinoma |
P08581
|
#142623 | Hirschsprung disease, susceptibility to, 1; hscr1 |
P07949
|
#609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
#146000 | Hypochondroplasia; hch |
P22607
|
#270450 | Insulin-like growth factor i, resistance to |
P08069
|
#307200 | Isolated growth hormone deficiency, type iii; ighd3 |
Q06187
|
#182000 | Keratosis, seborrheic |
P22607
|
#149730 | Lacrimoauriculodentodigital syndrome; ladd |
P22607
|
#601626 | Leukemia, acute myeloid; aml |
O60674
P10721 |
#211980 | Lung cancer |
P04626
|
#602849 | Muenke syndrome; mnkes |
P22607
|
#171400 | Multiple endocrine neoplasia, type iia; men2a |
P07949
|
#162300 | Multiple endocrine neoplasia, type iib; men2b |
P07949
|
#254450 | Myelofibrosis |
O60674
|
#254500 | Myeloma, multiple |
P22607
|
#613014 | Neuroblastoma, susceptibility to, 3; nblst3 |
Q9UM73
|
#162900 | Nevus, epidermal |
P22607
|
#167000 | Ovarian cancer |
P04626
|
#171300 | Pheochromocytoma |
P07949
|
#172800 | Piebald trait; pbt |
P10721
|
#262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
#263300 | Polycythemia vera; pv |
O60674
|
#191830 | Renal adysplasia |
P07949
|
#605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
#269840 | Selective t-cell defect; stcd |
P43403
|
#600802 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative |
P52333
|
#273300 | Testicular germ cell tumor; tgct |
P10721
P22607 |
#187600 | Thanatophoric dysplasia, type i; td1 |
P22607
|
#187601 | Thanatophoric dysplasia, type ii; td2 |
P22607
|
#614521 | Thrombocythemia 3; thcyt3 |
O60674
|
#155240 | Thyroid carcinoma, familial medullary; mtc |
P07949
|
#188550 | Thyroid carcinoma, papillary |
P07949
|
#611521 | Tyrosine kinase 2 deficiency |
P29597
|
KEGG | name | UniProt |
---|---|---|
H00012 | Polycythemia vera |
O60674
(related)
O60674 (marker) |
H00018 | Gastric cancer |
P04626
(related)
P08581 (related) |
H00019 | Pancreatic cancer |
P04626
(related)
|
H00022 | Bladder cancer |
P04626
(related)
P22607 (related) |
H00026 | Endometrial Cancer |
P04626
(related)
|
H00027 | Ovarian cancer |
P04626
(related)
|
H00028 | Choriocarcinoma |
P04626
(related)
|
H00030 | Cervical cancer |
P04626
(related)
|
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P08581 (related) |
H00719 | Leprechaunism |
P06213
(related)
|
H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
P43403 (related) |
H00032 | Thyroid cancer |
P07949
(related)
P07949 (marker) |
H00822 | Renal agenesis and Renal adysplasia |
P07949
(related)
|
H00910 | Hirschsprung disease (HD) |
P07949
(related)
|
H00916 | Congenital central hypoventilation syndrome (CCHS) |
P07949
(related)
|
H00015 | Malignant pleural mesothelioma |
P08069
(related)
|
H00050 | Synovial sarcoma |
P08069
(related)
|
H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
H00021 | Renal cell carcinoma |
P08581
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) |
H00170 | Piebaldism |
P10721
(related)
|
H00023 | Testicular cancer |
P10721
(marker)
|
H00010 | Multiple myeloma |
P22607
(related)
|
H00458 | Craniosynostosis |
P22607
(related)
|
H00505 | FGFR3-related short limb skeletal dysplasias |
P22607
(related)
|
H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P22607
(related)
|
H00997 | CATSHL syndrome |
P22607
(related)
|
H00107 | Other well-defined immunodeficiency syndromes |
P29597
(related)
|
H00523 | Noonan syndrome and related disorders |
P36507
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P43403
(marker)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P52333
(related)
|
H00085 | Agammaglobulinemias |
Q06187
(related)
|
H00254 | Pituitary Dwarfism (PD) |
Q06187
(related)
|
H00014 | Non-small cell lung cancer |
Q9UM73
(related)
|