PCIDB

KCF-S cluster No. 2301 (5 metabolites)

Plant Species

Cumulative plant class count

class name count
rosids 3
Liliopsida 1

Cumulative family count

class name count
Enterobacteriaceae 4
Brassicaceae 3
Poaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00000123 External link 512 2-phosphoglycerate
/ D-2-Phosphoglyceric acid
C00007286 External link 512 3-Phosphoglycerate
CHEMBL87788
CHEMBL1160563
C005156
2 / 1 / 1
C00007287 External link 512 3-Phosphoserine
CHEMBL284377
CHEMBL1418244
C046162
20 / 11 / 11
C00007385 External link 512 O-Phospho-L-homoserine
C00019551 External link 512 D-3-Phosphoglyceric acid
CHEMBL87788
CHEMBL1160563
2 / 1 / 1

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00558 Phosphoglycerate kinase 1 Enzyme C00007286 C00019551 1 / 1
P07205 Phosphoglycerate kinase 2 Enzyme C00007286 C00019551 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007287 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00007287 3 / 1
P00918 Carbonic anhydrase 2 Lyase C00007287 1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007287 0 / 1
Q14831 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor C00007287 0 / 0
P54132 Bloom syndrome protein Enzyme C00007287 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00007287 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00007287 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00007287 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00007287 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00007287 0 / 1
Q04609 Glutamate carboxypeptidase 2 M28B C00007287 0 / 0
Q14833 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor C00007287 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007287 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00007287 0 / 1
P22748 Carbonic anhydrase 4 Lyase C00007287 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00007287 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00007287 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00007287 2 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007287 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#300653 Phosphoglycerate kinase 1 deficiency P00558
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (12)

KEGG name UniProt
H00664 Anemia due to disorders of glycolytic enzymes P00558 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00021 Renal cell carcinoma Q16790 (marker)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)