PCIDB

KNApSAcK Metabolite C00007287

Metabolite

KNApSAcK Entry

id C00007287
Name 3-Phosphoserine
CAS RN 407-41-0
Standard InChI InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
Standard InChI (Main Layer) InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)

Cluster

Phytochemical cluster
KCF-S cluster No. 2301

Link

ChEMBL

By standard InChI CHEMBL284377
By standard InChI Main Layer CHEMBL284377 CHEMBL1418244

KEGG

By LinkDB C01005

CTD

By CAS RN C046162

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1
Enterobacteriaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Escherichia coli K12 83333 Enterobacteriaceae Bacteria

Human Protein / Gene in interaction

20 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL284377 CHEMBL1741321 (1)
1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL1418244 CHEMBL1794499 (1)
2 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL284377 CHEMBL828084 (1)
0 / 0
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL284377 CHEMBL1614554 (1)
3 / 1
P00918 Carbonic anhydrase 2 Lyase CHEMBL284377 CHEMBL828765 (1)
1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL284377 CHEMBL1741325 (1)
0 / 1
Q14831 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor CHEMBL284377 CHEMBL712460 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL284377 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL284377 CHEMBL1418244 CHEMBL1614458 (2)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL284377 CHEMBL1738606 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL284377 CHEMBL841750 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL284377 CHEMBL1741322 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL284377 CHEMBL829122 (1)
0 / 1
Q04609 Glutamate carboxypeptidase 2 M28B CHEMBL284377 CHEMBL888570 (1)
0 / 0
Q14833 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor CHEMBL284377 CHEMBL715495 (1) CHEMBL884506 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL284377 CHEMBL1613777 (1) CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL284377 CHEMBL1614108 (1) CHEMBL1613886 (1)
CHEMBL1741324 (1)
0 / 1
P22748 Carbonic anhydrase 4 Lyase CHEMBL284377 CHEMBL830248 (1)
1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL284377 CHEMBL1613914 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL284377 CHEMBL1614364 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (11)

KEGG disease name UniProt
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00021 Renal cell carcinoma Q16790 (marker)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)