KCF-S cluster No. 2359 (5 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 1 |
| rosids | 1 |
Cumulative family count
| class name | count |
|---|---|
| Sargassaceae | 4 |
| Sapindaceae | 1 |
| Asteraceae | 1 |
| Dictyotaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00024117
|
Sargatriol
|
|
||||
|
C00031300
|
Sargachromenol
|
CHEMBL1668777
CHEMBL1668778 |
7 / 7 / 10 |
|
||
|
C00041111
|
Sargaol
|
|
||||
|
C00048388
|
Fallachromenoic acid
/ (-)-Fallachromenoic acid |
|
||||
|
C00048531
|
Sargaol acetate
|
|
Human Protein / Gene in interactions
7 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10276 | Retinoic acid receptor alpha | NR1B1 | C00031300 | 1 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00031300 | 0 / 1 |
| P06401 | Progesterone receptor | NR3C3 | C00031300 | 0 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00031300 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00031300 | 1 / 1 |
| P08235 | Mineralocorticoid receptor | NR3C2 | C00031300 | 2 / 2 |
| P10275 | Androgen receptor | NR3C4 | C00031300 | 3 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612376 | Acute promyelocytic leukemia; apl |
P10276
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #605115 | Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy |
P08235
|
| #177735 | Pseudohypoaldosteronism, type i, autosomal dominant; pha1a |
P08235
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
P06401 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00243 | Hyperkalemic distal renal tubular acidosis (RTA type 4) |
P08235
(related)
|
| H00603 | Hypertension exacerbated in pregnancy |
P08235
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P10276
(related)
P10276 (marker) |
| H00516 | Isolated orofacial clefts |
P10276
(related)
|