class name | count |
---|
class name | count |
---|---|
Pleosporaceae | 5 |
Graphidaceae | 2 |
Corynesporascaceae | 2 |
Aspergillaceae | 1 |
Cordycipitaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00014943
![]() |
Gerfelin
/ QN 22074-5A |
![]() |
||||
C00023666
![]() |
Altenusin
|
CHEMBL483531
|
C095643
|
47 / 45 / 41 |
![]() |
|
C00032489
![]() |
Violaceol I
|
CHEMBL2000711
|
![]() |
|||
C00032490
![]() |
Violaceol II
|
CHEMBL1462570
|
25 / 13 / 10 |
![]() |
||
C00048364
![]() |
Corynether A
|
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00023666 C00032490 | 0 / 0 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00023666 C00032490 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00023666 C00032490 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00023666 C00032490 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00023666 C00032490 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00023666 C00032490 | 1 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00023666 C00032490 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00023666 C00032490 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00023666 C00032490 | 4 / 3 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00023666 C00032490 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00023666 C00032490 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00023666 C00032490 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00023666 C00032490 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00023666 C00032490 | 1 / 1 |
O75496 | Geminin | Unclassified protein | C00023666 C00032490 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00023666 C00032490 | 0 / 0 |
Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00032490 | 0 / 0 |
P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00023666 | 1 / 2 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00032490 | 2 / 0 |
P54760 | Ephrin type-B receptor 4 | Eph | C00023666 | 0 / 0 |
Q05397 | Focal adhesion kinase 1 | Fak | C00023666 | 0 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00032490 | 0 / 0 |
Q02763 | Angiopoietin-1 receptor | Tie | C00023666 | 1 / 1 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00023666 | 7 / 3 |
P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00023666 | 1 / 1 |
O60285 | NUAK family SNF1-like kinase 1 | CAMK serine/threonine protein kinase NUAK subfamily | C00023666 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00032490 | 1 / 2 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00032490 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00023666 | 0 / 0 |
P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00023666 | 5 / 4 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00023666 | 5 / 9 |
P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00023666 | 5 / 1 |
P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00023666 | 0 / 0 |
Q96GD4 | Aurora kinase B | Aur | C00023666 | 0 / 0 |
P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00023666 | 1 / 0 |
P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00023666 | 2 / 3 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00023666 | 0 / 0 |
P35916 | Vascular endothelial growth factor receptor 3 | Vegfr | C00023666 | 2 / 1 |
P41279 | Mitogen-activated protein kinase kinase kinase 8 | Ste11 | C00023666 | 0 / 0 |
P53350 | Serine/threonine-protein kinase PLK1 | PLK serine/threonine protein kinase subfamily | C00023666 | 0 / 0 |
P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00023666 | 4 / 1 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00023666 | 1 / 8 |
O00444 | Serine/threonine-protein kinase PLK4 | PLK serine/threonine protein kinase subfamily | C00023666 | 0 / 0 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00023666 | 0 / 0 |
P68400 | Casein kinase II subunit alpha | Ck2 | C00023666 | 0 / 0 |
P34949 | Mannose-6-phosphate isomerase | Enzyme | C00032490 | 1 / 1 |
P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00023666 | 1 / 3 |
P37840 | Alpha-synuclein | Unclassified protein | C00023666 | 4 / 2 |
O14965 | Aurora kinase A | Aur | C00023666 | 0 / 0 |
P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | C00023666 | 1 / 3 |
Q99700 | Ataxin-2 | Unclassified protein | C00032490 | 1 / 1 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00032490 | 1 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00023666 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00023666 | 1 / 4 |
Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00023666 | 0 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00032490 | 2 / 1 |
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
#615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
#114480 | Breast cancer |
P31749
|
#114500 | Colorectal cancer; crc |
P31749
P84022 Q14191 |
#602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
#615109 | Cowden syndrome 6; cws6 |
P31749
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
#125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
#246200 | Donohue syndrome |
P06213
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#602089 | Hemangioma, capillary infantile |
P35916
P35968 |
#114550 | Hepatocellular carcinoma |
P08581
|
#609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
#270450 | Insulin-like growth factor i, resistance to |
P08069
|
#607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
#601626 | Leukemia, acute myeloid; aml |
P09619
P36888 |
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P00533
P04626 |
#153100 | Lymphedema, hereditary, ia |
P35916
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
#131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
#228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#167000 | Ovarian cancer |
P04626
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P37840
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#176920 | Proteus syndrome |
P31749
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#600195 | Venous malformations, multiple cutaneous and mucosal; vmcm |
Q02763
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
|
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P08581 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P04626 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) P09619 (related) P11802 (related) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
H00019 | Pancreatic cancer |
P04626
(related)
|
H00026 | Endometrial Cancer |
P04626
(related)
|
H00027 | Ovarian cancer |
P04626
(related)
|
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P08581 (related) |
H00719 | Leprechaunism |
P06213
(related)
|
H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
H00015 | Malignant pleural mesothelioma |
P08069
(related)
|
H00050 | Synovial sarcoma |
P08069
(related)
|
H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
H00021 | Renal cell carcinoma |
P08581
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00101 | Other phagocyte defects |
P11413
(related)
|
H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
H00038 | Malignant melanoma |
P11802
(related)
|
H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
H00535 | Lymphedemas |
P35916
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00531 | Venous malformations |
Q02763
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|