Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Pleosporaceae 5
Graphidaceae 2
Corynesporascaceae 2
Aspergillaceae 1
Cordycipitaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00014943 External link 512 Gerfelin
/ QN 22074-5A
C00023666 External link 512 Altenusin
CHEMBL483531
C095643
47 / 45 / 41
C00032489 External link 512 Violaceol I
CHEMBL2000711
C00032490 External link 512 Violaceol II
CHEMBL1462570
25 / 13 / 10
C00048364 External link 512 Corynether A

Human Protein / Gene in interactions

56 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00023666 C00032490 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00023666 C00032490 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00023666 C00032490 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00023666 C00032490 0 / 0
P06746 DNA polymerase beta Enzyme C00023666 C00032490 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00023666 C00032490 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00023666 C00032490 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00023666 C00032490 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00023666 C00032490 4 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00023666 C00032490 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00023666 C00032490 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00023666 C00032490 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00023666 C00032490 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00023666 C00032490 1 / 1
O75496 Geminin Unclassified protein C00023666 C00032490 0 / 0
P39748 Flap endonuclease 1 Enzyme C00023666 C00032490 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00032490 0 / 0
P11413 Glucose-6-phosphate 1-dehydrogenase Enzyme C00023666 1 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00032490 2 / 0
P54760 Ephrin type-B receptor 4 Eph C00023666 0 / 0
Q05397 Focal adhesion kinase 1 Fak C00023666 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00032490 0 / 0
Q02763 Angiopoietin-1 receptor Tie C00023666 1 / 1
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00023666 7 / 3
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00023666 1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00023666 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00032490 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00032490 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00023666 0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00023666 5 / 4
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00023666 5 / 9
P09619 Platelet-derived growth factor receptor beta Pdgfr C00023666 5 / 1
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00023666 0 / 0
Q96GD4 Aurora kinase B Aur C00023666 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00023666 1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00023666 2 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00023666 0 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr C00023666 2 / 1
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 C00023666 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00023666 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00023666 4 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00023666 1 / 8
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00023666 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00023666 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00023666 0 / 0
P34949 Mannose-6-phosphate isomerase Enzyme C00032490 1 / 1
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00023666 1 / 3
P37840 Alpha-synuclein Unclassified protein C00023666 4 / 2
O14965 Aurora kinase A Aur C00023666 0 / 0
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00023666 1 / 3
Q99700 Ataxin-2 Unclassified protein C00032490 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00032490 1 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00023666 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00023666 1 / 4
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00023666 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00032490 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (50)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300908 Anemia, nonspherocytic hemolytic, due to g6pd deficiency P11413
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#114480 Breast cancer P31749
#114500 Colorectal cancer; crc P31749
P84022
Q14191
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#615109 Cowden syndrome 6; cws6 P31749
#127750 Dementia, lewy body; dlb P37840
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#246200 Donohue syndrome P06213
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#602089 Hemangioma, capillary infantile P35916
P35968
#114550 Hepatocellular carcinoma P08581
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#270450 Insulin-like growth factor i, resistance to P08069
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#601626 Leukemia, acute myeloid; aml P09619
P36888
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P00533
P04626
#153100 Lymphedema, hereditary, ia P35916
#174800 Mccune-albright syndrome; mas P63092
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#166350 Osseous heteroplasia, progressive; poh P63092
#167000 Ovarian cancer P04626
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#176920 Proteus syndrome P31749
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (45)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00019 Pancreatic cancer P04626 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00101 Other phagocyte defects P11413 (related)
H00668 Anemia due to disorders of glutathione metabolism P11413 (related)
H00038 Malignant melanoma P11802 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)