KCF-S cluster No. 2453 (4 metabolites)

Corresponding Phytochemical cluster No. 43


Plant Species


Cumulative plant class count

class name count
eudicotyledons 4
asterids 3
rosids 1

Cumulative family count

class name count
Menispermaceae 4
Lamiaceae 2
Euphorbiaceae 1
Asteraceae 1

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Clerodanes 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Clerodanes C09077 C00003417

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00003417 External link 512 Columbin
CHEMBL1417543
C062514
3 / 5 / 4
C00038609 External link 512 Blepharolide A
/ (-)-Blepharolide A
C00041828 External link 512 Salvisplendin A
/ (-)-Salvisplendin A
C00047368 External link 512 8-Epirhynchosperin A
/ (-)-8-Epirhynchosperin A
CHEMBL1086147
1 / 0 / 0

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00047368 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00003417 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003417 4 / 3
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003417 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (4)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)