KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000150 External link 512 D-beta-Phenyllactic acid
CHEMBL1778420
C00000750 External link 512 Phenylacetic acid
CHEMBL1044
C025136
3 / 1 / 1 3 / 0
C00035885 External link 512 Tropic acid
C00037426 External link 512 L-Mandelic acid
/ L-(+)-Mandelic acid
CHEMBL58910
CHEMBL292411
CHEMBL1609
12 / 15 / 11

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00037426 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00037426 0 / 0
P02545 Prelamin-A/C Unclassified protein C00037426 11 / 10
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00037426 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00037426 2 / 0
P15121 Aldose reductase Enzyme C00000750 0 / 0
P08107 Heat shock 70 kDa protein 1A/1B Unclassified protein C00037426 0 / 0
P27169 Serum paraoxonase/arylesterase 1 Enzyme C00000750 1 / 0
P35236 Tyrosine-protein phosphatase non-receptor type 7 Tyr C00037426 0 / 0
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00037426 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00037426 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00000750 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00037426 0 / 0
P11142 Heat shock cognate 71 kDa protein Unclassified protein C00037426 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00037426 1 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000750
5445 PON2 paraoxonase 2 (EC:3.1.1.2 3.1.1.81) C00000750
5446 PON3 paraoxonase 3 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000750

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#612633 Microvascular complications of diabetes, susceptibility to, 5; mvcd5 P27169
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (12)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)