| class name | count |
|---|---|
| rosids | 2 |
| asterids | 2 |
| class name | count |
|---|---|
| Fabaceae | 2 |
| Pseudomonadaceae | 1 |
| Lactobacillaceae | 1 |
| Enterobacteriaceae | 1 |
| Streptomycetaceae | 1 |
| Xylariaceae | 1 |
| Solanaceae | 1 |
| Adoxaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00000150
|
D-beta-Phenyllactic acid
|
CHEMBL1778420
|
|
|||
|
C00000750
|
Phenylacetic acid
|
CHEMBL1044
|
C025136
|
3 / 1 / 1 | 3 / 0 |
|
|
C00035885
|
Tropic acid
|
|
||||
|
C00037426
|
L-Mandelic acid
/ L-(+)-Mandelic acid |
CHEMBL58910
CHEMBL292411 CHEMBL1609 |
12 / 15 / 11 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00037426 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00037426 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00037426 | 11 / 10 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00037426 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00037426 | 2 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000750 | 0 / 0 |
| P08107 | Heat shock 70 kDa protein 1A/1B | Unclassified protein | C00037426 | 0 / 0 |
| P27169 | Serum paraoxonase/arylesterase 1 | Enzyme | C00000750 | 1 / 0 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00037426 | 0 / 0 |
| P98170 | E3 ubiquitin-protein ligase XIAP | Other cytosolic protein | C00037426 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00037426 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000750 | 0 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00037426 | 0 / 0 |
| P11142 | Heat shock cognate 71 kDa protein | Unclassified protein | C00037426 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00037426 | 1 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000750
|
| 5445 | PON2 | paraoxonase 2 (EC:3.1.1.2 3.1.1.81) |
C00000750
|
| 5446 | PON3 | paraoxonase 3 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000750
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #300635 | Lymphoproliferative syndrome, x-linked, 2; xlp2 |
P98170
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #612633 | Microvascular complications of diabetes, susceptibility to, 5; mvcd5 |
P27169
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P98170
(related)
|