KCF-S cluster No. 2531 (4 metabolites)

Corresponding Phytochemical cluster No. 63

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	4

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Cumulative family count

class name	count
Piperaceae	4

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
alpha-Pyrones	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
alpha-Pyrones	C09926	C00002988
alpha-Pyrones	C09952	C00003005

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002988	Dihydromethysticin	CHEMBL576066 CHEMBL1510786		11 / 2 / 3
C00003005	Methysticin	CHEMBL579224 CHEMBL1883024	C076881	10 / 14 / 40
C00029378	11-Hydroxy-12-methoxydihydrokavain
C00029583	Marindinin / 7,8-Dihydrokavain	CHEMBL569329 CHEMBL1338909	C113859	5 / 3 / 5

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002988 C00003005 C00029583	0 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002988 C00003005 C00029583	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002988 C00003005	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002988 C00029583	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002988 C00003005	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002988 C00003005	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002988 C00003005	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00003005	7 / 37
P10145	Interleukin-8	Secreted protein	C00029583	0 / 0
O75496	Geminin	Unclassified protein	C00002988	0 / 0
P03372	Estrogen receptor	NR3A1	C00002988	1 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00003005	3 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00002988	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00003005	4 / 1
P10275	Androgen receptor	NR3C4	C00029583	3 / 4
Q9UBT6	DNA polymerase kappa	Enzyme	C00003005	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002988	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions