KCF-S cluster No. 3086 (4 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	3

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Cumulative family count

class name	count
Brassicaceae	3
Mactridae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00007540	Sphinganine	CHEMBL448741 CHEMBL1442934 CHEMBL1487948	C005682	41 / 51 / 73	0 / 1
C00007541	Sphinganine-1-phosphate	CHEMBL78539 CHEMBL78494 CHEMBL311863		3 / 0 / 0
C00007543	4-Hydroxysphinganine	CHEMBL236036 CHEMBL466395		2 / 2 / 3
C00044752	ES-285 / Spisulosine 285	CHEMBL1835439

Human Protein / Gene in interactions

44 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	C00007540 C00007543	2 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00007540 C00007543	0 / 0
O75496	Geminin	Unclassified protein	C00007540	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00007540	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00007540	2 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00007540	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00007540	2 / 2
P06746	DNA polymerase beta	Enzyme	C00007540	0 / 0
P04062	Glucosylceramidase	Enzyme	C00007540	6 / 4
O95136	Sphingosine 1-phosphate receptor 2	EDG receptor	C00007541	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00007540	11 / 10
P11597	Cholesteryl ester transfer protein	Secreted protein	C00007540	1 / 1
P08183	Multidrug resistance protein 1	drug	C00007540	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00007540	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00007540	1 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00007540	1 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00007540	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00007540	2 / 2
P21453	Sphingosine 1-phosphate receptor 1	EDG receptor	C00007541	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00007540	0 / 0
P42858	Huntingtin	Unclassified protein	C00007540	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00007540	2 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00007540	7 / 37
Q9Y253	DNA polymerase eta	Enzyme	C00007540	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00007540	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00007540	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00007540	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00007540	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00007540	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00007540	0 / 1
P61088	Ubiquitin-conjugating enzyme E2 N	Enzyme	C00007540	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00007540	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007540	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00007540	0 / 0
Q99500	Sphingosine 1-phosphate receptor 3	EDG receptor	C00007541	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00007540	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00007540	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00007540	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00007540	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00007540	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00007540	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00007540	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00007540	1 / 4
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00007540	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions