KCF-S cluster No. 3393 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	2

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Cumulative family count

class name	count
Brassicaceae	2
Enterobacteriaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00007383	AICAR / 5-Amino-4-imidazolecarboxamide ribonucleotide	CHEMBL483849	C031143	6 / 2 / 2	21 / 3
C00007394	FAICAR / Phosphoribosyl-formamido-carboxamide / N-Formamidoimidazole-4-carboxamide ribonucleotide		C062030
C00019655	AIR (nucleotide) / Aminoimidazole ribonucleotide / 5-Amino-1-beta-D-ribofuranosyl-5'-(dihydrogen phosphate)-imidazole		C024828

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P42574	Caspase-3	C14	C00007383	0 / 0
P09467	Fructose-1,6-bisphosphatase 1	Enzyme	C00007383	1 / 1
P55211	Caspase-9	C14	C00007383	0 / 0
P31939	Bifunctional purine biosynthesis protein PURH	Enzyme	C00007383	1 / 1
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00007383	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00007383	0 / 0

21 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
31	ACACA, ACAC, ACACAD, ACC, ACC1, ACCA	acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14)	C00007383
32	ACACB, ACC2, ACCB, HACC275	acetyl-CoA carboxylase beta (EC:6.4.1.2 6.3.4.14)	C00007383
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00007383
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00007383
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00007383
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00007383
890	CCNA2, CCN1, CCNA	cyclin A2	C00007383
891	CCNB1, CCNB	cyclin B1	C00007383
8529	CYP4F2, CPF2	cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30)	C00007383
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00007383
1994	ELAVL1, ELAV1, HUR, Hua, MelG	ELAV like RNA binding protein 1	C00007383
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00007383
3643	INSR, CD220, HHF5	insulin receptor (EC:2.7.10.1)	C00007383
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00007383
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00007383
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00007383
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00007383
5563	PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA	protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)	C00007383
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00007383
6194	RPS6, S6	ribosomal protein S6	C00007383
6564	SLC15A1, HPECT1, HPEPT1, PEPT1	solute carrier family 15 (oligopeptide transporter), member 1	C00007383

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions