class name | count |
---|
class name | count |
---|---|
Streptomycetaceae | 3 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00002487
![]() |
PA 93
/ U 6391 / Novo-R / Albamix / Cathocin / Inamycin / Robiocina / Albamycin / Cathomycin / Novobiocin / Sirbiocina / Stilbiocina / Cardelmycin / Spheromycin / Streptonivicin / Antibiotic PA-93 / Crystallinic acid |
CHEMBL35025
CHEMBL1237121 CHEMBL1617799 CHEMBL1619419 CHEMBL1625763 CHEMBL2221247 |
D009675
|
14 / 8 / 1 | 2 / 1 |
![]() |
C00017954
![]() |
18631RP
/ RP 18631 / NSC 227186 / Clorobiocin / Chlorobiocin / Antibiotic 2562A |
CHEMBL303984
CHEMBL1172192 |
C006260
|
23 / 20 / 14 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q02880 | DNA topoisomerase 2-beta | Isomerase | C00002487 C00017954 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00017954 | 0 / 0 |
O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00002487 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00017954 | 1 / 1 |
P06746 | DNA polymerase beta | Enzyme | C00017954 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00017954 | 0 / 0 |
Q16543 | Hsp90 co-chaperone Cdc37 | Unclassified protein | C00002487 | 0 / 0 |
P02768 | Serum albumin | Secreted protein | C00002487 | 0 / 0 |
P11388 | DNA topoisomerase 2-alpha | Isomerase | C00002487 | 0 / 0 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00017954 | 2 / 2 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00017954 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00017954 | 2 / 0 |
O75496 | Geminin | Unclassified protein | C00017954 | 0 / 0 |
Q8TCC7 | Solute carrier family 22 member 8 | Antiporter | C00002487 | 0 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00017954 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00017954 | 7 / 3 |
Q9Y253 | DNA polymerase eta | Enzyme | C00017954 | 1 / 1 |
Q4U2R8 | Solute carrier family 22 member 6 | Antiporter | C00002487 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00017954 | 0 / 0 |
Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00002487 | 1 / 0 |
Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00002487 | 2 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00017954 | 0 / 0 |
P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00002487 | 0 / 0 |
Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00002487 | 1 / 0 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00017954 | 1 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00017954 | 0 / 0 |
P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002487 | 5 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00017954 | 4 / 3 |
P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00002487 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00017954 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002487 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00017954 | 1 / 0 |
Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00017954 | 0 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00017954 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00017954 | 1 / 4 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00017954 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
952 | CD38, T10 | CD38 molecule (EC:3.2.2.5) |
C00002487
|
1000 | CDH2, CD325, CDHN, CDw325, NCAD | cadherin 2, type 1, N-cadherin (neuronal) |
C00002487
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
#614490 | Blood group, junior system; jr |
Q9UNQ0
|
#114500 | Colorectal cancer; crc |
P84022
|
#218800 | Crigler-najjar syndrome, type i |
P22309
|
#606785 | Crigler-najjar syndrome, type ii |
P22309
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#143500 | Gilbert syndrome |
P22309
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
#237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H00208 | Hyperbilirubinemia |
P22309
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|