Plant Species


Cumulative plant class count

class name count
eudicotyledons 1
asterids 1

Cumulative family count

class name count
Parmeliaceae 3
Proteaceae 1
Asteraceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00039196 External link 512 Excelsione
/ Phomopsidone
CHEMBL426725
C00039870 External link 512 Norstictic acid
CHEMBL228281
15 / 14 / 17
C00040391 External link 512 Stictic acid
CHEMBL173530
30 / 22 / 24

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00039870 C00040391 2 / 2
O00255 Menin Unclassified protein C00039870 C00040391 2 / 5
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00039870 C00040391 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00039870 C00040391 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00039870 C00040391 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00039870 C00040391 4 / 3
P11473 Vitamin D3 receptor NR1I1 C00039870 C00040391 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00039870 C00040391 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00039870 C00040391 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00039870 C00040391 0 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00039870 C00040391 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00039870 C00040391 1 / 2
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00040391 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00040391 1 / 1
O75496 Geminin Unclassified protein C00040391 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00039870 2 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00040391 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00039870 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00040391 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00040391 0 / 0
P39748 Flap endonuclease 1 Enzyme C00040391 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00040391 1 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00040391 3 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00040391 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00040391 0 / 0
P29466 Caspase-1 C14 C00039870 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00040391 1 / 0
P06746 DNA polymerase beta Enzyme C00040391 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00040391 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00040391 1 / 4
P63165 Small ubiquitin-related modifier 1 Unclassified protein C00040391 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00040391 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00040391 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P18054
Q14191
#119900 Digital clubbing, isolated congenital P15428
#133239 Esophageal cancer P18054
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#613705 Orofacial cleft 10; ofc10 P63165
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (24)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00516 Isolated orofacial clefts P63165 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)