Plant Species


Cumulative plant class count

class name count
rosids 2

Cumulative family count

class name count
Brassicaceae 2
Streptomycetaceae 1
Enterobacteriaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000747 External link 512 L-S-methylcysteine
CHEMBL394875
1 / 1 / 0
C00001379 External link 512 L-Methionine
CHEMBL274119
CHEMBL42336
CHEMBL1234268
CHEMBL1770614
CHEMBL2106977
D008715
2 / 2 / 0 24 / 34
C00007594 External link 512 Dihomomethionine

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001379 2 / 0
P49327 Fatty acid synthase Transferase C00001379 0 / 0
P52732 Kinesin-like protein KIF11 Other cytosolic protein C00000747 1 / 0

24 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
383 ARG1 arginase 1 (EC:3.5.3.1) C00001379
396 ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1 Rho GDP dissociation inhibitor (GDI) alpha C00001379
635 BHMT, BHMT1 betaine--homocysteine S-methyltransferase (EC:2.1.1.5) C00001379
23743 BHMT2 betaine--homocysteine S-methyltransferase 2 (EC:2.1.1.10) C00001379
883 CCBL1, GTK, KAT1, KATI cysteine conjugate-beta lyase, cytoplasmic (EC:2.6.1.64 2.6.1.7 4.4.1.13) C00001379
1329 COX5B, COXVB cytochrome c oxidase subunit Vb (EC:1.9.3.1) C00001379
1398 CRK, CRKII, p38 v-crk avian sarcoma virus CT10 oncogene homolog C00001379
1508 CTSB, APPS, CPSB cathepsin B (EC:3.4.22.1) C00001379
54512 EXOSC4, RRP41, RRP41A, Rrp41p, SKI6, Ski6p, hRrp41p, p12A exosome component 4 C00001379
2739 GLO1, GLOD1, GLYI glyoxalase I (EC:4.4.1.5) C00001379
2947 GSTM3, GST5, GSTB, GSTM3-3, GTM3 glutathione S-transferase mu 3 (brain) (EC:2.5.1.18) C00001379
9446 GSTO1, GSTO_1-1, GSTTLp28, P28, SPG-R glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2) C00001379
3176 HNMT, HMT, HNMT-S1, HNMT-S2 histamine N-methyltransferase (EC:2.1.1.8) C00001379
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00001379
9588 PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29 peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15) C00001379
81876 RAB1B RAB1B, member RAS oncogene family C00001379
9367 RAB9A, RAB9 RAB9A, member RAS oncogene family C00001379
6519 SLC3A1, ATR1, CSNU1, D2H, NBAT, RBAT solute carrier family 3 (amino acid transporter heavy chain), member 1 C00001379
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00001379
6723 SRM, PAPT, SPDSY, SPS1, SRML1 spermidine synthase (EC:2.5.1.16) C00001379
6748 SSR4, TRAPD signal sequence receptor, delta C00001379
7411 VBP1, PFD3, PFDN3, VBP-1 von Hippel-Lindau binding protein 1 C00001379
51699 VPS29, DC15, PEP11 vacuolar protein sorting 29 homolog (S. cerevisiae) (EC:3.1.3.3) C00001379
7450 VWF, F8VWF, VWD von Willebrand factor C00001379

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#152950 Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation; mclmr P52732
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798

Diseases related to CTD interactions

34 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001321 Autistic Disorder C00001379
D006528 Carcinoma, Hepatocellular C00001379
D006332 Cardiomegaly C00001379
D002659 Child Development Disorders, Pervasive C00001379
D019970 Cocaine-Related Disorders C00001379
D003128 COMA C00001379
D003711 Demyelinating Diseases C00001379
D004195 Disease Models, Animal C00001379
D056486 Drug-Induced Liver Injury C00001379
D005234 Fatty Liver C00001379
D005235 Fatty Liver, Alcoholic C00001379
D005327 Fetal Resorption C00001379
D005910 Glioma C00001379
D034381 Hearing Loss C00001379
D006501 Hepatic Encephalopathy C00001379
D006505 Hepatitis C00001379
D006529 Hepatomegaly C00001379
D020138 HYPERHOMOCYSTEINEMIA C00001379
D007249 Inflammation C00001379
D007669 Kidney Calculi C00001379
D007674 Kidney Diseases C00001379
D007859 Learning Disorders C00001379
D008103 Liver Cirrhosis C00001379
D008106 Liver Cirrhosis, Experimental C00001379
D008107 Liver Diseases C00001379
D008569 Memory Disorders C00001379
D008661 Metabolism, Inborn Errors C00001379
C541083 Non-alcoholic Fatty Liver Disease C00001379
D020335 Paraparesis C00001379
D011041 Poisoning C00001379
D012559 Schizophrenia C00001379
D012640 Seizures C00001379
D016136 Spina Bifida Occulta C00001379
D013118 Spinal Cord Diseases C00001379