KCF-S cluster No. 3630 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Methanobacteriaceae	2
Methanosarcinaceae	2
Axinellidae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000761	Coenzyme M	CHEMBL1098319
C00000762	S-Methyl coenzyme M
C00048188	Taurine	CHEMBL239243	D013654	14 / 21 / 19	55 / 38

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00048188	1 / 0
P04062	Glucosylceramidase	Enzyme	C00048188	6 / 4
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00048188	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00048188	11 / 10
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00048188	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00048188	1 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00048188	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00048188	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00048188	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00048188	0 / 0
Q7Z2H8	Proton-coupled amino acid transporter 1	Unclassified protein	C00048188	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00048188	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00048188	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00048188	1 / 0

55 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
27	ABL2, ABLL, ARG	c-abl oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2)	C00048188
55803	ADAP2, CENTA2, HSA272195, cent-b	ArfGAP with dual PH domains 2	C00048188
135	ADORA2A, A2aR, ADORA2, RDC8	adenosine A2a receptor	C00048188
147	ADRA1B, ADRA1, ALPHA1BAR	adrenoceptor alpha 1B	C00048188
637	BID, FP497	BH3 interacting domain death agonist	C00048188
659	BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK	bone morphogenetic protein receptor, type II (serine/threonine kinase) (EC:2.7.11.30)	C00048188
10486	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	C00048188
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00048188
1123	CHN1, ARHGAP2, CHN, DURS2, NC, RHOGAP2	chimerin 1	C00048188
9318	COPS2, ALIEN, CSN2, SGN2, TRIP15	COP9 signalosome subunit 2	C00048188
2833	CXCR3, CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR	chemokine (C-X-C motif) receptor 3	C00048188
23576	DDAH1, DDAH	dimethylarginine dimethylaminohydrolase 1 (EC:3.5.3.18)	C00048188
8525	DGKZ, DAGK5, DAGK6, DGK-ZETA, hDGKzeta	diacylglycerol kinase, zeta (EC:2.7.1.107)	C00048188
9538	EI24, EPG4, PIG8, TP53I8	etoposide induced 2.4	C00048188
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00048188
2260	FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1	fibroblast growth factor receptor 1 (EC:2.7.10.1)	C00048188
2741	GLRA1, HKPX1, STHE	glycine receptor, alpha 1	C00048188
2917	GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7	glutamate receptor, metabotropic 7	C00048188
2982	GUCY1A3, GC-SA3, GUC1A3, GUCA3, GUCSA3, GUCY1A1	guanylate cyclase 1, soluble, alpha 3 (EC:4.6.1.2)	C00048188
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00048188
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00048188
889	KRIT1, CAM, CCM1	KRIT1, ankyrin repeat containing	C00048188
10314	LANCL1, GPR69A, p40	LanC lantibiotic synthetase component C-like 1 (bacterial)	C00048188
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00048188
64231	MS4A6A, 4SPAN3, 4SPAN3.2, CD20L3, MS4A6, MST090, MSTP090	membrane-spanning 4-domains, subfamily A, member 6A	C00048188
81285	OR51E2, OR51E3P, OR52A2, PSGR	olfactory receptor, family 51, subfamily E, member 2	C00048188
55824	PAG1, CBP, PAG	phosphoprotein associated with glycosphingolipid microdomains 1	C00048188
10298	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4 (EC:2.7.11.1)	C00048188
5423	POLB	polymerase (DNA directed), beta (EC:2.7.7.7)	C00048188
5424	POLD1, CDC2, CRCS10, MDPL, POLD	polymerase (DNA directed), delta 1, catalytic subunit (EC:2.7.7.7)	C00048188
27434	POLM, Pol_Mu, Tdt-N	polymerase (DNA directed), mu (EC:2.7.7.7)	C00048188
26051	PPP1R16B, ANKRD4, TIMAP	protein phosphatase 1, regulatory subunit 16B	C00048188
5529	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	C00048188
5577	PRKAR2B, PRKAR2, RII-BETA	protein kinase, cAMP-dependent, regulatory, type II, beta (EC:2.7.11.1)	C00048188
5664	PSEN2, AD3L, AD4, CMD1V, PS2, STM2	presenilin 2 (Alzheimer disease 4)	C00048188
5796	PTPRK, R-PTP-kappa	protein tyrosine phosphatase, receptor type, K (EC:3.1.3.48)	C00048188
5868	RAB5A, RAB5	RAB5A, member RAS oncogene family	C00048188
5889	RAD51C, BROVCA3, FANCO, R51H3, RAD51L2	RAD51 paralog C	C00048188
5883	RAD9A, RAD9	RAD9 homolog A (S. pombe) (EC:3.1.11.2)	C00048188
9693	RAPGEF2, CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, RA-GEF-1, Rap-GEP, nRap_GEP	Rap guanine nucleotide exchange factor (GEF) 2	C00048188
10125	RASGRP1, CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	C00048188
6196	RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3	ribosomal protein S6 kinase, 90kDa, polypeptide 2 (EC:2.7.11.1)	C00048188
6447	SCG5, 7B2, P7B2, SGNE1, SgV	secretogranin V (7B2 protein)	C00048188
9126	SMC3, BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1	structural maintenance of chromosomes 3	C00048188
10302	SNAPC5, SNAP19	small nuclear RNA activating complex, polypeptide 5, 19kDa	C00048188
10253	SPRY2, hSPRY2	sprouty homolog 2 (Drosophila)	C00048188
6729	SRP54	signal recognition particle 54kDa	C00048188
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00048188
6869	TACR1, NK1R, NKIR, SPR, TAC1R	tachykinin receptor 1	C00048188
7010	TEK, CD202B, TIE-2, TIE2, VMCM, VMCM1	TEK tyrosine kinase, endothelial (EC:2.7.10.1)	C00048188
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00048188
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00048188
7297	TYK2, JTK1	tyrosine kinase 2 (EC:2.7.10.2)	C00048188
7415	VCP, ALS14, IBMPFD, IBMPFD1, TERA, p97	valosin containing protein (EC:3.6.4.6)	C00048188
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00048188

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions