KCF-S cluster No. 3693 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	1

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Cumulative family count

class name	count
Polyangiaceae	1
Araceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00016759	Fenozan / Fenoxan / Fenoksan / Phenoxan / Phenosan / Phenozan / Fenozan acid / Irganox 1310
C00036446	2-(4-Hydroxyphenyl)-1-nitroethane
C00042069	2,6-bis(1,1-Dimethylethyl)-4-methylphenol	CHEMBL146	D002084	21 / 11 / 11	33 / 40

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00042069	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00042069	4 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00042069	2 / 2
P06746	DNA polymerase beta	Enzyme	C00042069	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00042069	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00042069	1 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00042069	0 / 1
P11473	Vitamin D3 receptor	NR1I1	C00042069	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00042069	0 / 0
O75496	Geminin	Unclassified protein	C00042069	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00042069	0 / 0
P10145	Interleukin-8	Secreted protein	C00042069	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00042069	0 / 0
P07384	Calpain-1 catalytic subunit	C2	C00042069	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00042069	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00042069	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00042069	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00042069	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00042069	0 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00042069	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00042069	0 / 0

33 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00042069
59	ACTA2, AAT6, ACTSA, MYMY5	actin, alpha 2, smooth muscle, aorta	C00042069
335	APOA1	apolipoprotein A-I	C00042069
336	APOA2, Apo-AII, ApoA-II, apoAII	apolipoprotein A-II	C00042069
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00042069
523	ATP6V1A, ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (EC:3.6.3.14)	C00042069
760	CA2, CA-II, CAC, CAII, Car2	carbonic anhydrase II (EC:4.2.1.1)	C00042069
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00042069
4513	COX2, COII, MTCO2, MT-CO2	cytochrome c oxidase subunit II	C00042069
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00042069
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00042069
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00042069
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00042069
4018	LPA, AK38, APOA, LP	lipoprotein, Lp(a) (EC:3.4.21.-)	C00042069
7376	NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR	nuclear receptor subfamily 1, group H, member 2	C00042069
10062	NR1H3, LXR-a, LXRA, RLD-1	nuclear receptor subfamily 1, group H, member 3	C00042069
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00042069
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00042069
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00042069
5230	PGK1, MIG10, PGKA	phosphoglycerate kinase 1 (EC:2.7.2.3)	C00042069
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00042069
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00042069
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00042069
778733			C00042069
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00042069
5706	PSMC6, CADP44, P44, SUG2, p42	proteasome (prosome, macropain) 26S subunit, ATPase, 6	C00042069
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00042069
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00042069
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00042069
51106	TFB1M, CGI75, mtTFB, mtTFB1	transcription factor B1, mitochondrial (EC:2.1.1.-)	C00042069
64216	TFB2M, Hkp1, mtTFB2	transcription factor B2, mitochondrial	C00042069
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00042069
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00042069

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions