KNApSAcK Metabolite C00042069
Metabolite
KNApSAcK Entry
| id | C00042069 |
|---|---|
| Name | 2,6-bis(1,1-Dimethylethyl)-4-methylphenol |
| CAS RN | 128-37-0 |
| Standard InChI | InChI=1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3 |
| Standard InChI (Main Layer) | InChI=1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 3693 |
Link
ChEMBL
| By standard InChI | CHEMBL146 |
|---|---|
| By standard InChI Main Layer | CHEMBL146 |
KEGG
| By LinkDB | C14693 |
|---|
CTD
| By CAS RN | D002084 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Microcystis aeruginosa | 1126 | Bacteria |
Human Protein / Gene in interaction
21 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL146 |
CHEMBL2071965
(1)
|
1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | CHEMBL146 |
CHEMBL1613842
(1)
|
4 / 2 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL146 |
CHEMBL1794573
(1)
|
2 / 2 |
| P06746 | DNA polymerase beta | Enzyme | CHEMBL146 |
CHEMBL1614079
(1)
|
0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL146 |
CHEMBL1794371
(2)
|
0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL146 |
CHEMBL956075
(1)
|
1 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL146 |
CHEMBL2071963
(1)
|
0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL146 |
CHEMBL1794311
(1)
|
2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL146 |
CHEMBL1614458
(1)
|
0 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL146 |
CHEMBL2114780
(1)
|
0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | CHEMBL146 |
CHEMBL1908086
(1)
|
0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | CHEMBL146 |
CHEMBL2114835
(1)
|
0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | CHEMBL146 |
CHEMBL956074
(1)
|
0 / 0 |
| P07384 | Calpain-1 catalytic subunit | C2 | CHEMBL146 |
CHEMBL659381
(1)
CHEMBL654083
(1)
|
0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | CHEMBL146 |
CHEMBL1794437
(1)
|
0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL146 |
CHEMBL2071962
(1)
|
0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | CHEMBL146 |
CHEMBL2114853
(1)
|
0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL146 |
CHEMBL2071964
(1)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL146 |
CHEMBL2071966
(1)
CHEMBL2071967
(1)
|
0 / 1 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | CHEMBL146 |
CHEMBL1908083
(1)
|
0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | CHEMBL146 |
CHEMBL2114915
(1)
|
0 / 0 |
CTD interaction (55)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D002084 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | [Butylated Hydroxytoluene co-treated with iron(II)-ascorbic acid complex] results in increased expression of ABCA1 protein |
affects cotreatment
/ increases expression |
protein |
17070507
|
| D002084 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of ABCA1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17070507
|
| D002084 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of ABCA1 protein] |
decreases expression
/ decreases reaction |
protein |
17070507
|
| D002084 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | Butylated Hydroxytoluene results in increased expression of ABCA1 mRNA |
increases expression
|
mRNA |
17070507
|
| D002084 | 59 |
ACTA2
AAT6 ACTSA MYMY5 |
actin, alpha 2, smooth muscle, aorta | Butylated Hydroxytoluene inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] |
decreases reaction
/ increases expression |
protein |
16757516
|
| D002084 | 335 |
APOA1
|
apolipoprotein A-I | [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein] |
affects cotreatment
/ decreases reaction / increases oxidation |
protein |
12576517
|
| D002084 | 335 |
APOA1
|
apolipoprotein A-I | Butylated Hydroxytoluene inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein] |
decreases reaction
/ increases oxidation |
protein |
12576517
|
| D002084 | 336 |
APOA2
Apo-AII ApoA-II apoAII |
apolipoprotein A-II | [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein] |
affects cotreatment
/ decreases reaction / increases oxidation |
protein |
12576517
|
| D002084 | 336 |
APOA2
Apo-AII ApoA-II apoAII |
apolipoprotein A-II | Butylated Hydroxytoluene inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein] |
decreases reaction
/ increases oxidation |
protein |
12576517
|
| D002084 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | Butylated Hydroxytoluene inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] |
affects binding
/ decreases reaction / increases activity |
protein |
10696776
|
| D002084 | 523 |
ATP6V1A
ATP6A1 ATP6V1A1 HO68 VA68 VPP2 Vma1 |
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (EC:3.6.3.14) | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein] |
decreases expression
/ decreases reaction |
protein |
12470298
|
| D002084 | 760 |
CA2
CA-II CAC CAII Car2 |
carbonic anhydrase II (EC:4.2.1.1) | Butylated Hydroxytoluene results in decreased activity of CA2 protein |
decreases activity
|
protein |
19231207
|
| D002084 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased activity of CASP3 protein |
affects cotreatment
/ decreases activity |
protein |
14981915
|
| D002084 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Butylated Hydroxytoluene results in decreased activity of CASP3 protein |
decreases activity
|
protein |
14981915
|
| D002084 | 4513 |
COX2
COII MTCO2 MT-CO2 |
cytochrome c oxidase subunit II | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of COX2 protein] |
decreases expression
/ decreases reaction |
protein |
12470298
|
| D002084 | 1555 |
CYP2B6
CPB6 CYP2B CYP2B7 CYP2B7P CYPIIB6 EFVM IIB1 P450 |
cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) | Butylated Hydroxytoluene results in increased expression of CYP2B6 mRNA |
increases expression
|
mRNA |
18570159
|
| D002084 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | Butylated Hydroxytoluene results in increased expression of CYP3A4 mRNA |
increases expression
|
mRNA |
18570159
|
| D002084 | 2152 |
F3
CD142 TF TFA |
coagulation factor III (thromboplastin, tissue factor) | Butylated Hydroxytoluene inhibits the reaction [Copper results in increased activity of F3 protein] |
decreases reaction
/ increases activity |
protein |
7600656
|
| D002084 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Butylated Hydroxytoluene affects the expression of HMOX1 mRNA |
affects expression
|
mRNA |
8743975
|
| D002084 | 4018 |
LPA
AK38 APOA LP |
lipoprotein, Lp(a) (EC:3.4.21.-) | Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in decreased expression of PLAT protein] |
decreases expression
/ decreases reaction |
protein |
10856522
|
| D002084 | 4018 |
LPA
AK38 APOA LP |
lipoprotein, Lp(a) (EC:3.4.21.-) | Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in increased expression of PLAT protein] |
decreases reaction
/ increases expression |
protein |
10856522
|
| D002084 | 4018 |
LPA
AK38 APOA LP |
lipoprotein, Lp(a) (EC:3.4.21.-) | Butylated Hydroxytoluene inhibits the reaction [LPA protein results in decreased expression of SERPINE1 protein] |
decreases expression
/ decreases reaction |
protein |
10856522
|
| D002084 | 4018 |
LPA
AK38 APOA LP |
lipoprotein, Lp(a) (EC:3.4.21.-) | Butylated Hydroxytoluene inhibits the reaction [LPA protein results in increased expression of SERPINE1 protein] |
decreases reaction
/ increases expression |
protein |
10856522
|
| D002084 | 7376 |
NR1H2
LXR-b LXRB NER NER-I RIP15 UNR |
nuclear receptor subfamily 1, group H, member 2 | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of NR1H2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17070507
|
| D002084 | 10062 |
NR1H3
LXR-a LXRA RLD-1 |
nuclear receptor subfamily 1, group H, member 3 | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of NR1H3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17070507
|
| D002084 | 9970 |
NR1I3
CAR CAR1 MB67 |
nuclear receptor subfamily 1, group I, member 3 | Butylated Hydroxytoluene binds to and results in decreased activity of NR1I3 protein alternative form |
affects binding
/ decreases activity |
protein |
20869355
|
| D002084 | 9970 |
NR1I3
CAR CAR1 MB67 |
nuclear receptor subfamily 1, group I, member 3 | Butylated Hydroxytoluene binds to and results in increased activity of NR1I3 protein alternative form |
affects binding
/ increases activity |
protein |
20869355
|
| D002084 | 4968 |
OGG1
HMMH HOGG1 MUTM OGH1 |
8-oxoguanine DNA glycosylase (EC:4.2.99.18) | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of OGG1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
20676402
|
| D002084 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | Butylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein] |
decreases reaction
/ increases activity |
protein |
2126186
|
| D002084 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein] |
decreases reaction
/ increases activity |
protein |
2126186
|
| D002084 | 5230 |
PGK1
MIG10 PGKA |
phosphoglycerate kinase 1 (EC:2.7.2.3) | Butylated Hydroxytoluene inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] |
decreases reaction
/ increases expression |
protein |
18603805
|
| D002084 | 5327 |
PLAT
T-PA TPA |
plasminogen activator, tissue (EC:3.4.21.68) | Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in decreased expression of PLAT protein] |
decreases expression
/ decreases reaction |
protein |
10856522
|
| D002084 | 5327 |
PLAT
T-PA TPA |
plasminogen activator, tissue (EC:3.4.21.68) | Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in increased expression of PLAT protein] |
decreases reaction
/ increases expression |
protein |
10856522
|
| D002084 | 5444 |
PON1
ESA MVCD5 PON |
paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) | Butylated Hydroxytoluene inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein] |
affects cotreatment
/ decreases expression / decreases reaction |
protein |
16052486
|
| D002084 | 5445 |
PON2
|
paraoxonase 2 (EC:3.1.1.2 3.1.1.81) | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of PON2 protein] |
decreases reaction
/ increases expression |
protein |
17916643
|
| D002084 | 778733 | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of PPAR mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17070507
|
||
| D002084 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in decreased expression of PPARG mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17070507
|
| D002084 | 5706 |
PSMC6
CADP44 P44 SUG2 p42 |
proteasome (prosome, macropain) 26S subunit, ATPase, 6 | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
12470298
|
| D002084 | 5054 |
SERPINE1
PAI PAI-1 PAI1 PLANH1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Butylated Hydroxytoluene inhibits the reaction [LPA protein results in decreased expression of SERPINE1 protein] |
decreases expression
/ decreases reaction |
protein |
10856522
|
| D002084 | 5054 |
SERPINE1
PAI PAI-1 PAI1 PLANH1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Butylated Hydroxytoluene inhibits the reaction [LPA protein results in increased expression of SERPINE1 protein] |
decreases reaction
/ increases expression |
protein |
10856522
|
| D002084 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | [Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased expression of SOD2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
14981915
|
| D002084 | 7019 |
TFAM
MTTF1 MTTFA TCF6 TCF6L1 TCF6L2 TCF6L3 |
transcription factor A, mitochondrial | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFAM mRNA] |
decreases reaction
/ increases expression |
mRNA |
20676402
|
| D002084 | 7019 |
TFAM
MTTF1 MTTFA TCF6 TCF6L1 TCF6L2 TCF6L3 |
transcription factor A, mitochondrial | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFAM protein] |
decreases reaction
/ increases expression |
protein |
20676402
|
| D002084 | 51106 |
TFB1M
CGI75 mtTFB mtTFB1 |
transcription factor B1, mitochondrial (EC:2.1.1.-) | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFB1M mRNA] |
decreases reaction
/ increases expression |
mRNA |
20676402
|
| D002084 | 51106 |
TFB1M
CGI75 mtTFB mtTFB1 |
transcription factor B1, mitochondrial (EC:2.1.1.-) | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFB1M protein] |
decreases reaction
/ increases expression |
protein |
20676402
|
| D002084 | 64216 |
TFB2M
Hkp1 mtTFB2 |
transcription factor B2, mitochondrial | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFB2M mRNA] |
decreases reaction
/ increases expression |
mRNA |
20676402
|
| D002084 | 64216 |
TFB2M
Hkp1 mtTFB2 |
transcription factor B2, mitochondrial | Butylated Hydroxytoluene inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of TFB2M protein] |
decreases reaction
/ increases expression |
protein |
20676402
|
| D002084 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Butylated Hydroxytoluene inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] |
decreases reaction
/ increases expression |
protein |
16757516
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases reaction
/ increases expression |
mRNA |
9721806
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
9721806
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein] |
decreases expression
/ decreases reaction |
protein |
12470298
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of COX2 protein] |
decreases expression
/ decreases reaction |
protein |
12470298
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA] |
decreases expression
/ decreases reaction |
protein |
12470298
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene results in decreased expression of TNF protein |
decreases expression
|
protein |
9721806
|
| D002084 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Butylated Hydroxytoluene results in increased susceptibility to TNF protein |
increases response to substance
|
protein |
16910777
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (11)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (11)
| KEGG | disease name | UniProt |
|---|---|---|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
Q16637 (related) |
Diseases related to CTD interactions
40 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D000014 | D002084 | Abnormalities, Drug-Induced |
marker/mechanism
|
7191588
|
|
| D058186 | D002084 | Acute Kidney Injury |
marker/mechanism
|
277130
3395247 |
|
| D000236 | D002084 | Adenoma |
marker/mechanism
|
6500233
6592388 |
|
| D018248 | D002084 | Adenoma, Liver Cell |
marker/mechanism
|
3128505
3804114 3804118 3949264 6659972 |
|
| D000435 | D002084 | Alcoholic Intoxication |
therapeutic
|
8723618
|
|
| D001145 | D002084 | Arrhythmias, Cardiac |
therapeutic
|
8723618
|
|
| D001649 | D002084 | Bile Duct Diseases |
marker/mechanism
|
3026937
|
|
| D006528 | D002084 | Carcinoma, Hepatocellular |
marker/mechanism
|
3804114
3804118 3949264 6659972 |
|
| D009202 | D002084 | Cardiomyopathies |
therapeutic
|
2361559
4094316 |
|
| D002543 | D002084 | Cerebral Hemorrhage |
marker/mechanism
|
7419139
|
|
| D003110 | D002084 | Colonic Neoplasms |
marker/mechanism
|
3945967
|
|
| D003876 | D002084 | Dermatitis, Atopic |
marker/mechanism
|
15218738
|
|
| D056486 | D002084 | Drug-Induced Liver Injury |
marker/mechanism
|
3026937
3395247 |
|
| D064420 | D002084 | Drug-Related Side Effects and Adverse Reactions |
marker/mechanism
|
2370251
7419139 |
|
| D020964 | D002084 | Embryo Loss |
marker/mechanism
|
3949264
|
|
| D005355 | D002084 | Fibrosis |
marker/mechanism
|
3026937
|
|
| D005770 | D002084 | Gastrointestinal Neoplasms |
marker/mechanism
|
3804115
|
|
| D006130 | D002084 | Growth Disorders |
marker/mechanism
|
3804114
3949264 6659972 7286863 |
|
| D006331 | D002084 | Heart Diseases |
therapeutic
|
6626733
|
|
| D006402 | D002084 | Hematologic Diseases |
marker/mechanism
|
7286863
|
|
| D006470 | D002084 | Hemorrhage |
marker/mechanism
|
7419139
|
|
| D006474 | D002084 | Hemorrhagic Disorders |
marker/mechanism
|
7419139
|
|
| D006529 | D002084 | Hepatomegaly |
marker/mechanism
|
3026937
|
|
| D006965 | D002084 | Hyperplasia |
marker/mechanism
|
3026937
|
|
| D006967 | D002084 | Hypersensitivity |
marker/mechanism
|
17604070
|
|
| D007674 | D002084 | Kidney Diseases |
marker/mechanism
|
1555799
|
|
| D007683 | D002084 | Kidney Tubular Necrosis, Acute |
marker/mechanism
|
3395247
|
|
| D008113 | D002084 | Liver Neoplasms |
marker/mechanism
therapeutic |
1906380
3804115 3945967 6680729 6704970 10503899 18177683 |
|
| D008175 | D002084 | Lung Neoplasms |
marker/mechanism
|
6592388
11246140 11696405 15390079 16337739 18597497 19359593 19925653 20101149 |
|
| D008325 | D002084 | Mammary Neoplasms, Experimental |
therapeutic
|
1500032
|
|
| D009336 | D002084 | Necrosis |
marker/mechanism
therapeutic |
2006506
12085349 |
|
| D009369 | D002084 | Neoplasms |
marker/mechanism
|
3026937
|
|
| D010190 | D002084 | Pancreatic Neoplasms |
therapeutic
|
1906380
|
|
| D010212 | D002084 | Papilloma |
marker/mechanism
|
1752781
6500233 |
|
| D011014 | D002084 | Pneumonia |
marker/mechanism
|
11893704
|
|
| D011230 | D002084 | Precancerous Conditions |
marker/mechanism
therapeutic |
1752781
1906380 3128505 3802071 6135514 |
|
| D011297 | D002084 | Prenatal Exposure Delayed Effects |
marker/mechanism
|
7191588
|
|
| D011507 | D002084 | Proteinuria |
marker/mechanism
|
3395247
|
|
| D013964 | D002084 | Thyroid Neoplasms |
marker/mechanism
|
6500233
6680729 |
|
| D001749 | D002084 | Urinary Bladder Neoplasms |
marker/mechanism
|
1752781
1906380 3802071 6135514 6500233 6536604 6680729 6704970 7889841 |