| Organism name | Microcystis aeruginosa |
|---|---|
| Genus | |
| Family | |
| Kingdom |
| Linked NCBI taxonomy name | Microcystis aeruginosa |
|---|---|
| Linked NCBI taxonomy ID | 1126 |
| Linked level | species |
| Family in NCBI taxonomy | |
|---|---|
| ID |
| Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
|---|---|
| ID | 2 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00047516
|
Micropeptin F
/ (-)-Micropeptin F |
No. 116 |
|
|||||
|
C00045342
|
Micropeptin EI 964
|
CHEMBL256742
|
No. 116 |
|
||||
|
C00045343
|
Micropeptin EI 992
/ (-)-Micropeptin EI 992 |
CHEMBL255290
|
No. 116 |
|
||||
|
C00047513
|
Micropeptin C
/ (-)-Micropeptin C |
CHEMBL540722
|
1 / 4 / 2 | No. 116 |
|
|||
|
C00047515
|
Micropeptin E
/ (-)-Micropeptin E |
No. 116 |
|
|||||
|
C00047514
|
Micropeptin D
/ (-)-Micropeptin D |
CHEMBL541960
|
1 / 4 / 2 | No. 116 |
|
|||
|
C00003112
|
Cedrol
/ (+)-Cedrol / alpha-Cedrol |
CHEMBL1592444
CHEMBL1974890 |
C078669
|
5 / 14 / 11 | No. 161 | No. 38 |
|
|
|
C00003194
|
Thujopsene
|
No. 365 | No. 38 |
|
||||
|
C00022931
|
Aphanizophyll
/ 3',4'-Didehydro-1,2'-dihydro-1',3,4-trihydroxy-beta,epsilon-caroten-2-yl alpha-L-mannopyranoside |
No. 394 |
|
|||||
|
C00030472
|
Heptadecane
|
C016486
|
No. 599 |
|
||||
|
C00001265
|
Pentadecane
|
CHEMBL1234557
|
C033245
|
2 / 8 / 37 | No. 599 |
|
||
|
C00030879
|
Octadecane
|
C022883
|
No. 732 |
|
||||
|
C00030165
|
Eicosane
|
C050821
|
No. 732 |
|
||||
|
C00030827
|
Nonadecane
|
C061580
|
No. 732 |
|
||||
|
C00028580
|
Microcyclamide
|
CHEMBL503451
|
No. 1240 |
|
||||
|
C00028582
|
Microginin 299B
|
No. 1877 |
|
|||||
|
C00028581
|
Microginin 299A
|
No. 1877 |
|
|||||
|
C00029816
|
beta-Ionone
|
CHEMBL559945
|
No. 2480 | No. 38 |
|
|||
|
C00028587
|
Micropeptin 478-A
|
No. 2582 |
|
|||||
|
C00028588
|
Micropeptin 478-B
|
No. 2582 |
|
|||||
|
C00026878
|
Microcin SF608
|
CHEMBL2011686
CHEMBL2011687 |
1 / 4 / 2 | No. 2841 |
|
|||
|
C00045213
|
Aeruginosin EI 461
/ (+)-Aeruginosin EI 461 |
CHEMBL559914
|
No. 2841 |
|
||||
|
C00042069
|
2,6-bis(1,1-Dimethylethyl)-4-methylphenol
|
CHEMBL146
|
D002084
|
21 / 11 / 11 | 33 / 40 | No. 3693 |
|
|
|
C00046345
|
Radiosumin B
/ (+)-Radiosumin B |
CHEMBL478092
|
1 / 1 / 2 | No. 3758 |
|
|||
|
C00042278
|
beta-Cyclocitral
|
CHEMBL1952257
|
1 / 2 / 2 | No. 4106 | No. 38 |
|
||
|
C00001259
|
Naphthalene
|
CHEMBL16293
|
C031721
|
6 / 5 / 4 | 43 / 18 | No. 5021 |
|
|
|
C00042578
|
Henicosane
|
No. 5813 |
|
|||||
|
C00042472
|
DIethyl phthalate
|
CHEMBL388558
|
C007379
|
10 / 10 / 8 | 9 / 7 | No. 6057 |
|
|
|
C00042866
|
Propanoic acid 2-methyl-3-hydroxy-2,4,4-trimethylpentyl ester
|
No. 7905 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00001259 C00042069 C00042472 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00026878 C00047513 C00047514 | 4 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001259 C00042069 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00001259 C00042472 | 3 / 4 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003112 C00042069 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00042069 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00042069 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00042472 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003112 | 11 / 10 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00042472 | 3 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003112 | 3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00042069 | 0 / 0 |
| P42574 | Caspase-3 | C14 | C00001259 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00042069 | 1 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00042069 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00042069 | 2 / 3 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00042069 | 1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001259 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00042472 | 2 / 0 |
| P00747 | Plasminogen | S1A | C00046345 | 1 / 2 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00042069 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00042069 | 2 / 2 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00042069 | 0 / 0 |
| P07384 | Calpain-1 catalytic subunit | C2 | C00042069 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00042472 | 0 / 0 |
| P04000 | Long-wave-sensitive opsin 1 | Unclassified protein | C00042278 | 2 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00042472 | 0 / 1 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00001259 | 2 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00042069 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003112 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00042069 | 4 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00001265 | 1 / 1 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00042069 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003112 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00042069 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00042069 | 0 / 1 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00042069 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00042472 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001265 | 7 / 37 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00042069 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00042472 | 1 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00042472 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00001259
C00042472
|
| 367 | AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | androgen receptor |
C00042069
C00042472
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00042069
C00042472
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001259
C00042472
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001259
C00042069
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00042069
C00042472
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001259
C00042472
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00042069
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00042472
|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00001259
|
| 429 | ASCL1, ASH1, HASH1, MASH1, bHLHa46 | achaete-scute family bHLH transcription factor 1 |
C00001259
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001259
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001259
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001259
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001259
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00001259
|
| 1558 | CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 | cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1) |
C00001259
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00001259
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00001259
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001259
|
| 13107 |
C00001259
|
||
| 29785 | CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 (EC:1.14.14.1) |
C00001259
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00042472
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00001259
|
| 2052 | EPHX1, EPHX, EPOX, HYL1, MEH | epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) |
C00001259
|
| 2053 | EPHX2, CEH, SEH | epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) |
C00001259
|
| 2252 | FGF7, HBGF-7, KGF | fibroblast growth factor 7 |
C00001259
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00001259
|
| 2521 | FUS, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS | fused in sarcoma |
C00001259
|
| 2642 | GCGR, GGR | glucagon receptor |
C00001259
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00001259
|
| 8870 | IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 | immediate early response 3 |
C00001259
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00001259
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00001259
|
| 3956 | LGALS1, GAL1, GBP | lectin, galactoside-binding, soluble, 1 |
C00001259
|
| 4157 | MC1R, CMM5, MSH-R, SHEP2 | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
C00001259
|
| 4159 | MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL | melanocortin 3 receptor |
C00001259
|
| 4160 | MC4R | melanocortin 4 receptor |
C00001259
|
| 4161 | MC5R, MC2 | melanocortin 5 receptor |
C00001259
|
| 10403 | NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80 | NDC80 kinetochore complex component |
C00001259
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00001259
|
| 5053 | PAH, PH, PKU, PKU1 | phenylalanine hydroxylase (EC:1.14.16.1) |
C00001259
|
| 5894 | RAF1, CRAF, NS5, Raf-1, c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) |
C00001259
|
| 389 | RHOC, ARH9, ARHC, H9, RHOH9 | ras homolog family member C |
C00001259
|
| 7356 | SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1 | secretoglobin, family 1A, member 1 (uteroglobin) |
C00001259
|
| 6855 | SYP, MRXSYP | synaptophysin |
C00001259
|
| 6932 | TCF7, TCF-1 | transcription factor 7 (T-cell specific, HMG-box) |
C00001259
|
| 7076 | TIMP1, CLGI, EPA, EPO, HCI, TIMP | TIMP metallopeptidase inhibitor 1 |
C00001259
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001259
|
| 19 | ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD | ATP-binding cassette, sub-family A (ABC1), member 1 |
C00042069
|
| 59 | ACTA2, AAT6, ACTSA, MYMY5 | actin, alpha 2, smooth muscle, aorta |
C00042069
|
| 335 | APOA1 | apolipoprotein A-I |
C00042069
|
| 336 | APOA2, Apo-AII, ApoA-II, apoAII | apolipoprotein A-II |
C00042069
|
| 523 | ATP6V1A, ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (EC:3.6.3.14) |
C00042069
|
| 760 | CA2, CA-II, CAC, CAII, Car2 | carbonic anhydrase II (EC:4.2.1.1) |
C00042069
|
| 4513 | COX2, COII, MTCO2, MT-CO2 | cytochrome c oxidase subunit II |
C00042069
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00042069
|
| 2152 | F3, CD142, TF, TFA | coagulation factor III (thromboplastin, tissue factor) |
C00042069
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00042472
|
| 4018 | LPA, AK38, APOA, LP | lipoprotein, Lp(a) (EC:3.4.21.-) |
C00042069
|
| 7376 | NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR | nuclear receptor subfamily 1, group H, member 2 |
C00042069
|
| 10062 | NR1H3, LXR-a, LXRA, RLD-1 | nuclear receptor subfamily 1, group H, member 3 |
C00042069
|
| 4968 | OGG1, HMMH, HOGG1, MUTM, OGH1 | 8-oxoguanine DNA glycosylase (EC:4.2.99.18) |
C00042069
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00042069
|
| 5230 | PGK1, MIG10, PGKA | phosphoglycerate kinase 1 (EC:2.7.2.3) |
C00042069
|
| 5327 | PLAT, T-PA, TPA | plasminogen activator, tissue (EC:3.4.21.68) |
C00042069
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00042069
|
| 5445 | PON2 | paraoxonase 2 (EC:3.1.1.2 3.1.1.81) |
C00042069
|
| 778733 |
C00042069
|
||
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00042069
|
| 5706 | PSMC6, CADP44, P44, SUG2, p42 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
C00042069
|
| 5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00042069
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00042069
|
| 7019 | TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 | transcription factor A, mitochondrial |
C00042069
|
| 51106 | TFB1M, CGI75, mtTFB, mtTFB1 | transcription factor B1, mitochondrial (EC:2.1.1.-) |
C00042069
|
| 64216 | TFB2M, Hkp1, mtTFB2 | transcription factor B2, mitochondrial |
C00042069
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00042069
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00042069
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #303700 | Blue cone monochromacy; bcm |
P04000
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #303900 | Colorblindness, partial, protan series; cbp |
P04000
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
P00747 (related) |
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00974 | Blue cone monochromacy |
P04000
(related)
|
| H00976 | Colorblindness |
P04000
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D006529 | Hepatomegaly |
C00042472
C00001259 C00042069 |
| D018248 | Adenoma, Liver Cell |
C00042472
C00042069 |
| D056486 | Drug-Induced Liver Injury |
C00042472
C00042069 |
| D008175 | Lung Neoplasms |
C00001259
C00042069 |
| D009336 | Necrosis |
C00001259
C00042069 |
| D006965 | Hyperplasia |
C00001259
C00042069 |
| D011041 | Poisoning |
C00042472
C00001259 |
| D000014 | Abnormalities, Drug-Induced |
C00001259
C00042069 |
| D058186 | Acute Kidney Injury |
C00001259
C00042069 |
| D006528 | Carcinoma, Hepatocellular |
C00042069
|
| D000743 | Anemia, Hemolytic |
C00001259
|
| D002386 | Cataract |
C00001259
|
| D006456 | Hemoglobinuria |
C00001259
|
| D006959 | Hyperoxaluria |
C00001259
|
| D008548 | Melanosis |
C00042472
|
| D008114 | Liver Neoplasms, Experimental |
C00001259
|
| D055370 | Lung Injury |
C00001259
|
| D005234 | Fatty Liver |
C00042472
|
| D048629 | Micronuclei, Chromosome-Defective |
C00001259
|
| D001943 | Breast Neoplasms |
C00042472
|
| D009362 | Neoplasm Metastasis |
C00001259
|
| D014133 | Tracheal Diseases |
C00001259
|
| D015431 | Weight Loss |
C00001259
|
| D000236 | Adenoma |
C00042069
|
| D000435 | Alcoholic Intoxication |
C00042069
|
| D001145 | Arrhythmias, Cardiac |
C00042069
|
| D001649 | Bile Duct Diseases |
C00042069
|
| D055371 | Acute Lung Injury |
C00001259
|
| D009202 | Cardiomyopathies |
C00042069
|
| D002543 | Cerebral Hemorrhage |
C00042069
|
| D003110 | Colonic Neoplasms |
C00042069
|
| D003876 | Dermatitis, Atopic |
C00042069
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00042069
|
| D020964 | Embryo Loss |
C00042069
|
| D005355 | Fibrosis |
C00042069
|
| D005770 | Gastrointestinal Neoplasms |
C00042069
|
| D006130 | Growth Disorders |
C00042069
|
| D006331 | Heart Diseases |
C00042069
|
| D006402 | Hematologic Diseases |
C00042069
|
| D006470 | Hemorrhage |
C00042069
|
| D006474 | Hemorrhagic Disorders |
C00042069
|
| D006967 | Hypersensitivity |
C00042069
|
| D007674 | Kidney Diseases |
C00042069
|
| D007683 | Kidney Tubular Necrosis, Acute |
C00042069
|
| D008113 | Liver Neoplasms |
C00042069
|
| D008325 | Mammary Neoplasms, Experimental |
C00042069
|
| D009369 | Neoplasms |
C00042069
|
| D010190 | Pancreatic Neoplasms |
C00042069
|
| D010212 | Papilloma |
C00042069
|
| D011014 | Pneumonia |
C00042069
|
| D011230 | Precancerous Conditions |
C00042069
|
| D011297 | Prenatal Exposure Delayed Effects |
C00042069
|
| D011507 | Proteinuria |
C00042069
|
| D013964 | Thyroid Neoplasms |
C00042069
|
| D001749 | Urinary Bladder Neoplasms |
C00042069
|