PCIDB

KCF-S cluster No. 6057 (1 metabolites)

Plant Species

Cumulative plant class count

class name count

Cumulative family count

class name count

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00042472 External link 512 DIethyl phthalate
CHEMBL388558
C007379
10 / 10 / 8 9 / 7

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00042472 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00042472 3 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00042472 2 / 0
O75496 Geminin Unclassified protein C00042472 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00042472 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00042472 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00042472 0 / 0
P10275 Androgen receptor NR3C4 C00042472 3 / 4
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00042472 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00042472 1 / 1

9 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00042472
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00042472
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00042472
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00042472
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00042472
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00042472
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00042472
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00042472
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00042472

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 O75874
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (8)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

7 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D018248 Adenoma, Liver Cell C00042472
D001943 Breast Neoplasms C00042472
D056486 Drug-Induced Liver Injury C00042472
D005234 Fatty Liver C00042472
D006529 Hepatomegaly C00042472
D008548 Melanosis C00042472
D011041 Poisoning C00042472