KCF-S cluster No. 371 (19 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
eudicotyledons	21
rosids	11
asterids	1

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Cumulative family count

class name	count
Berberidaceae	20
Rutaceae	6
Fabaceae	5
Asteraceae	1
Platanaceae	1
Umbilicariaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00005804	Phellatin
C00005805	Ikarisoside A	CHEMBL1728934	C092398	4 / 2 / 2
C00005806	Epimedoside C
C00005818	Icariside II / Baohuoside 1 / 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one	CHEMBL497293 CHEMBL560116	C060988	2 / 1 / 1	9 / 0
C00005819	Icariside I	CHEMBL558499
C00005833	Icaritin 3-rhamnoside
C00005834	Amurensin	CHEMBL454069		1 / 4 / 2
C00005835	Caohuoside C / 8-Prenylquercetin 4'-methyl ether 3-rhamnoside / 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
C00005836	Ikarisoside E
C00005837	6'',6''-Dimethylpyraono[2'',3'':7,8]kaempferol 4'-methyl ether 3-rhamnoside
C00006053	Ikarisoside D	CHEMBL1600141		4 / 4 / 1
C00014007	Caohuoside D / 8-(3''-Hydroxy-3''-methylbutyl)kaempferol 4'-methyl ether 7-glucoside / 7-(beta-D-Glucopyranosyloxy)-3,5-dihydroxy-8-(3-methoxy-3-methylbutyl)-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
C00019187	7,5'-Dihydroxy-5,4'-dimethoxy-3'-prenylisoflavone 7-O-galactoside
C00019255	Genisteone / 5,7,4'-Trihydroxy-6-prenylisoflavone 7-O-glucoside
C00019437	Auriculatin 4'-O-glucoside / 5,2'-Dihydroxy-8-prenyl-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavone 4'-O-glucoside
C00019701	Iuteone 7-O-glucoside / 5,7,2',4'-Tetrahydroxy-6-prenylisoflavone 7-O-glucoside
C00019702	Iicoisoflavone A 7-O-glucoside / 5,7,2',4'-Tetrahydroxy-3'-prenylisoflavone 7-O-glucoside
C00019703	Iicoisoflavone A 4'-O-glucoside / 5,7,2',4'-Tetrahydroxy-3'-prenylisoflavone 4'-O-glucoside
C00037971	Umbilicaxanthoside A

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75164	Lysine-specific demethylase 4A	Enzyme	C00005805 C00006053	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00005818	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00006053	2 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00005805	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00005834	4 / 2
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00005805	2 / 2
Q99700	Ataxin-2	Unclassified protein	C00006053	1 / 1
P61088	Ubiquitin-conjugating enzyme E2 N	Enzyme	C00005805	0 / 0
P51160	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	PDE_6C	C00005818	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00006053	1 / 0

9 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00005818
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00005818
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00005818
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00005818
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00005818
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00005818
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00005818
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00005818
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00005818

Related Diseases

Diseases related to proteins in ChEMBL interactions