Plant Species


Cumulative plant class count

class name count
rosids 3

Cumulative family count

class name count
Brassicaceae 3
Enterobacteriaceae 3

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001374 External link 512 L-isoleucine
CHEMBL297800
CHEMBL56053
CHEMBL1233584
CHEMBL1720399
CHEMBL1867019
CHEMBL1869615
4 / 2 / 0
C00001377 External link 512 L-Leucine
CHEMBL46575
CHEMBL291962
CHEMBL1232258
12 / 18 / 14
C00001398 External link 512 L-Valine
CHEMBL11257
CHEMBL43068
CHEMBL1232398
5 / 12 / 14

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein C00001374 C00001377 C00001398 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001374 C00001377 2 / 0
P02545 Prelamin-A/C Unclassified protein C00001377 C00001398 11 / 10
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00001377 3 / 1
Q9Y263 Phospholipase A-2-activating protein Unclassified protein C00001377 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001377 0 / 1
Q92830 Histone acetyltransferase KAT2A Enzyme C00001374 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00001377 0 / 0
P46059 Solute carrier family 15 member 1 Dipeptide C00001398 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001377 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001377 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001377 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001377 1 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001374 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001398 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001398 1 / 4
Q05BR4 SLC16A10 protein Unclassified protein C00001377 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798

KEGG DISEASE (18)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00213 Hypophosphatasia P05186 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)