KCF-S cluster No. 4209 (3 metabolites)

Corresponding Phytochemical cluster No. 1

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
Magnoliophyta	13

---

Cumulative family count

class name	count
Piperaceae	13

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Piperidine alkaloids	1

---

metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Piperidine alkaloids	C03882	C00002065

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002065	Piperine / Bioperine / 1-Piperoylpiperidine	CHEMBL43185 CHEMBL1395862		32 / 47 / 64
C00002076	Trichostachine	CHEMBL1087296
C00034476	Dehydropipernonaline	CHEMBL483708 CHEMBL525259	C051966	1 / 1 / 2

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002065	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002065	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00002065	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00002065	1 / 1
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00002065	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002065	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00002065	3 / 2
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002065	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002065	1 / 1
P08183	Multidrug resistance protein 1	drug	C00002065	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002065	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002065	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002065	2 / 2
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002065	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002065	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002065	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002065	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002065	5 / 3
Q8NER1	Transient receptor potential cation channel subfamily V member 1	TRPV (Vanilloid)	C00002065	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002065	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002065	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002065	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002065	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002065	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002065	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002065	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002065	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002065	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002065	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002065	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00002065	0 / 0
P05362	Intercellular adhesion molecule 1	Adhesion	C00034476	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002065	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions