KCF-S cluster No. 4414 (2 metabolites)

Corresponding Phytochemical cluster No. 35


Plant Species


Cumulative plant class count

class name count
Spermatophyta 1
asterids 1

Cumulative family count

class name count
Pinaceae 1
Lamiaceae 1

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Cyclic monoterpenes 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Cyclic monoterpenes C11924 C00010870

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00010869 External link 512 Limonenecarboxylic acid
C00010870 External link 512 (+-)-Perrillic acid
CHEMBL1256620
CHEMBL1373981
C078706
11 / 18 / 18 2 / 0

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00010870 1 / 0
P02545 Prelamin-A/C Unclassified protein C00010870 11 / 10
P16473 Thyrotropin receptor Glycohormone receptor C00010870 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00010870 0 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00010870 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00010870 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00010870 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00010870 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00010870 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00010870 0 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00010870 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00010870
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00010870

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#612219 Ewing sarcoma; es P11308
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (18)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)