KCF-S cluster No. 480 (16 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (16)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Didymellaceae	14
Pleosporaceae	7
Xylariaceae	7
Hypocreaceae	1
Gnomoniaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (16)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00011321	Cytochalasin A		C031218
C00011322	Phomin / Cytochalasin B	CHEMBL56897 CHEMBL411729 CHEMBL1422227 CHEMBL1554187	D003571	20 / 22 / 18	13 / 0
C00011364	Deoxaphomin		C007249
C00011365	Proxiphomin		C009097
C00011366	Protophomin		C009092
C00011367	Ascochalasin
C00036993	Cytochalasin I / (-)-Cytochalasin I
C00036994	Cytochalasin II
C00036995	Cytochalasin III
C00036996	Cytochalasin IV
C00036997	Cytochalasin T
C00036998	Cytochalasin Z1
C00036999	Cytochalasin Z2
C00044679	Cytochalasin Z3
C00044680	Cytochalasin Z4	CHEMBL467209
C00044681	Cytochalasin Z5	CHEMBL512971

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q16637	Survival motor neuron protein	Unclassified protein	C00011322	4 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00011322	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00011322	1 / 1
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00011322	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00011322	11 / 10
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00011322	1 / 1
P20701	Integrin alpha-L	Membrane receptor	C00011322	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00011322	2 / 0
O75496	Geminin	Unclassified protein	C00011322	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00011322	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00011322	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00011322	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00011322	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00011322	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00011322	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00011322	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00011322	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00011322	1 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00011322	0 / 3
Q06710	Paired box protein Pax-8	Unclassified protein	C00011322	1 / 2

13 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
727	C5, C5a, C5b, CPAMD4	complement component 5	C00011322
847	CAT	catalase (EC:1.11.1.6)	C00011322
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00011322
1991	ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1	elastase, neutrophil expressed (EC:3.4.21.37)	C00011322
2056	EPO, EP, MVCD2	erythropoietin	C00011322
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00011322
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00011322
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00011322
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00011322
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00011322
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00011322
6515	SLC2A3, GLUT3	solute carrier family 2 (facilitated glucose transporter), member 3	C00011322
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00011322

Related Diseases

Diseases related to proteins in ChEMBL interactions