KCF-S cluster No. 4941 (2 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Aspergillaceae	3
Trichocomaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00023672	Wortmannin	CHEMBL428496 CHEMBL295038 CHEMBL1418590 CHEMBL1474372	C009687	131 / 97 / 89	122 / 11
C00023673	11-Deacetoxywortmannin	CHEMBL13513	C007272

Human Protein / Gene in interactions

131 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00023672	1 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00023672	0 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00023672	1 / 1
P42338	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Enzyme	C00023672	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00023672	7 / 37
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00023672	0 / 0
Q8TDX7	Serine/threonine-protein kinase Nek7	Nek	C00023672	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00023672	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00023672	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00023672	2 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00023672	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00023672	2 / 2
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00023672	0 / 0
Q15759	Mitogen-activated protein kinase 11	p38	C00023672	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00023672	0 / 0
O15530	3-phosphoinositide-dependent protein kinase 1	Pdk1	C00023672	0 / 0
P41240	Tyrosine-protein kinase CSK	Csk	C00023672	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00023672	1 / 1
P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Enzyme	C00023672	9 / 1
P45984	Mitogen-activated protein kinase 9	Jnk	C00023672	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00023672	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00023672	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00023672	0 / 0
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00023672	0 / 0
Q8IWQ3	Serine/threonine-protein kinase BRSK2	CAMK serine/threonine protein kinase BRSK subfamily	C00023672	0 / 0
P27448	MAP/microtubule affinity-regulating kinase 3	CAMK serine/threonine protein kinase MARK subfamily	C00023672	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00023672	11 / 10
P37840	Alpha-synuclein	Unclassified protein	C00023672	4 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00023672	3 / 1
Q05513	Protein kinase C zeta type	Iota	C00023672	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00023672	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00023672	0 / 1
P23443	Ribosomal protein S6 kinase beta-1	p70	C00023672	0 / 0
Q9UQB9	Aurora kinase C	Aur	C00023672	1 / 1
Q9HBH9	MAP kinase-interacting serine/threonine-protein kinase 2	CAMK serine/threonine protein kinase MNK subfamily	C00023672	0 / 0
Q9NQU5	Serine/threonine-protein kinase PAK 6	STE serine/threonine protein kinase PAKB subfamily	C00023672	0 / 0
Q16644	MAP kinase-activated protein kinase 3	CAMK serine/threonine protein kinase MAPKAPK	C00023672	0 / 0
Q9H422	Homeodomain-interacting protein kinase 3	CMGC dual-specificity kinase HIPK	C00023672	0 / 0
Q14680	Maternal embryonic leucine zipper kinase	Melk	C00023672	0 / 0
Q9NYY3	Serine/threonine-protein kinase PLK2	Plk2	C00023672	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00023672	1 / 0
P11473	Vitamin D3 receptor	NR1I1	C00023672	2 / 3
Q15746	Myosin light chain kinase, smooth muscle	Mlck	C00023672	1 / 1
Q13188	Serine/threonine-protein kinase 3	STE serine/threonine protein kinase MST subfamily	C00023672	0 / 0
P31751	RAC-beta serine/threonine-protein kinase	Akt	C00023672	2 / 2
O75582	Ribosomal protein S6 kinase alpha-5	CAMK serine/threonine protein kinase MSKB subfamily	C00023672	0 / 0
O14920	Inhibitor of nuclear factor kappa-B kinase subunit beta	Other serine/threonine protein kinase	C00023672	0 / 0
Q16513	Serine/threonine-protein kinase N2	Pkn	C00023672	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00023672	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00023672	0 / 0
Q8N5S9	Calcium/calmodulin-dependent protein kinase kinase 1	META serine/threonine protein kinase subfamily	C00023672	0 / 0
Q9P286	Serine/threonine-protein kinase PAK 7	STE serine/threonine protein kinase PAKB subfamily	C00023672	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00023672	0 / 0
Q96SB4	SRSF protein kinase 1	Srpk	C00023672	0 / 0
Q92630	Dual specificity tyrosine-phosphorylation-regulated kinase 2	CMGC dual-specificity kinase DYRK2	C00023672	0 / 0
O43781	Dual specificity tyrosine-phosphorylation-regulated kinase 3	CMGC dual-specificity kinase DYRK2	C00023672	0 / 0
O96013	Serine/threonine-protein kinase PAK 4	STE serine/threonine protein kinase PAKB subfamily	C00023672	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00023672	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00023672	2 / 0
O75496	Geminin	Unclassified protein	C00023672	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00023672	0 / 0
Q15418	Ribosomal protein S6 kinase alpha-1	Rskb	C00023672	0 / 0
O15264	Mitogen-activated protein kinase 13	p38	C00023672	0 / 0
P53779	Mitogen-activated protein kinase 10	Jnk	C00023672	0 / 1
Q9H1R3	Myosin light chain kinase 2, skeletal/cardiac muscle	Mlck	C00023672	1 / 0
P51955	Serine/threonine-protein kinase Nek2	Nek	C00023672	0 / 0
Q96RR4	Calcium/calmodulin-dependent protein kinase kinase 2	META serine/threonine protein kinase subfamily	C00023672	0 / 0
Q9H4B4	Serine/threonine-protein kinase PLK3	PLK serine/threonine protein kinase subfamily	C00023672	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00023672	7 / 3
Q9BUB5	MAP kinase-interacting serine/threonine-protein kinase 1	CAMK serine/threonine protein kinase MNK subfamily	C00023672	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00023672	1 / 2
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00023672	1 / 2
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00023672	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00023672	0 / 0
P48730	Casein kinase I isoform delta	Ck1	C00023672	1 / 0
Q96GD4	Aurora kinase B	Aur	C00023672	0 / 0
P49137	MAP kinase-activated protein kinase 2	CAMK serine/threonine protein kinase MAPKAPK	C00023672	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00023672	0 / 0
P45983	Mitogen-activated protein kinase 8	Jnk	C00023672	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00023672	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00023672	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00023672	2 / 2
Q01453	Peripheral myelin protein 22	Unclassified protein	C00023672	5 / 2
P53350	Serine/threonine-protein kinase PLK1	PLK serine/threonine protein kinase subfamily	C00023672	0 / 0
Q8IW41	MAP kinase-activated protein kinase 5	CAMK serine/threonine protein kinase MAPKAPK	C00023672	0 / 0
O75116	Rho-associated protein kinase 2	Rock	C00023672	0 / 0
O00329	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Enzyme	C00023672	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00023672	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00023672	0 / 0
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00023672	4 / 1
Q15118	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	Pdhk	C00023672	0 / 0
O00141	Serine/threonine-protein kinase Sgk1	AGC serine/threonine protein kinase SGK subfamily	C00023672	0 / 0
P51812	Ribosomal protein S6 kinase alpha-3	Rskb	C00023672	2 / 2
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00023672	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00023672	0 / 1
Q9HC98	Serine/threonine-protein kinase Nek6	Nek	C00023672	0 / 0
Q9H2X6	Homeodomain-interacting protein kinase 2	CMGC dual-specificity kinase HIPK	C00023672	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00023672	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00023672	1 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00023672	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00023672	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00023672	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00023672	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00023672	0 / 1
O96017	Serine/threonine-protein kinase Chk2	Rad53	C00023672	4 / 1
Q14012	Calcium/calmodulin-dependent protein kinase type 1	Camk1	C00023672	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00023672	0 / 0
P48736	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Enzyme	C00023672	0 / 0
P17612	cAMP-dependent protein kinase catalytic subunit alpha	Pka	C00023672	0 / 0
Q13627	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	CMGC dual-specificity kinase DYRK1	C00023672	1 / 0
P53778	Mitogen-activated protein kinase 12	p38	C00023672	0 / 0
O00418	Eukaryotic elongation factor 2 kinase	Atypical serine/threonine protein kinase alpha subfamily	C00023672	0 / 0
Q8TD08	Mitogen-activated protein kinase 15	Mapk	C00023672	0 / 0
Q86V86	Serine/threonine-protein kinase pim-3	Pim	C00023672	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00023672	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00023672	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00023672	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00023672	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00023672	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00023672	1 / 0
O00255	Menin	Unclassified protein	C00023672	2 / 5
P20248	Cyclin-A2	Other cytosolic protein	C00023672	0 / 0
P78396	Cyclin-A1	Other cytosolic protein	C00023672	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00023672	0 / 0
P68400	Casein kinase II subunit alpha	Ck2	C00023672	0 / 0
P19784	Casein kinase II subunit alpha'	Ck2	C00023672	0 / 0
P67870	Casein kinase II subunit beta	REG serine/threonine protein kinase family	C00023672	0 / 0
P27986	Phosphatidylinositol 3-kinase regulatory subunit alpha	Enzyme	C00023672	2 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00023672	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00023672	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00023672	1 / 1

122 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00023672
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00023672
248	ALPI, IAP	alkaline phosphatase, intestinal (EC:3.1.3.1)	C00023672
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00023672
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00023672
581	BAX, BCL2L4	BCL2-associated X protein	C00023672
9564	BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas	breast cancer anti-estrogen resistance 1	C00023672
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00023672
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00023672
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00023672
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00023672
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00023672
727	C5, C5a, C5b, CPAMD4	complement component 5	C00023672
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00023672
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00023672
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00023672
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00023672
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00023672
894	CCND2, KIAK0002	cyclin D2	C00023672
1232	CCR3, CC-CKR-3, CD193, CKR3, CMKBR3	chemokine (C-C motif) receptor 3	C00023672
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00023672
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00023672
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00023672
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00023672
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00023672
11200	CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1	checkpoint kinase 2 (EC:2.7.11.1)	C00023672
80781	COL18A1, KNO, KNO1, KS	collagen, type XVIII, alpha 1	C00023672
1278	COL1A2, OI4	collagen, type I, alpha 2	C00023672
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00023672
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00023672
2920	CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2	chemokine (C-X-C motif) ligand 2	C00023672
3579	CXCR2, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB	chemokine (C-X-C motif) receptor 2	C00023672
199974	CYP4Z1, CYP4A20	cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1)	C00023672
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00023672
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00023672
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00023672
2057	EPOR, EPO-R	erythropoietin receptor	C00023672
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00023672
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00023672
2252	FGF7, HBGF-7, KGF	fibroblast growth factor 7	C00023672
2308	FOXO1, FKH1, FKHR, FOXO1A	forkhead box O1	C00023672
2309	FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A	forkhead box O3	C00023672
4303	FOXO4, AFX, AFX1, MLLT7	forkhead box O4	C00023672
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00023672
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00023672
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00023672
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00023672
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00023672
3297	HSF1, HSTF1	heat shock transcription factor 1	C00023672
692420			C00023672
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00023672
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00023672
3458	IFNG, IFG, IFI	interferon, gamma	C00023672
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00023672
3592	IL12A, CLMF, IL-12A, NFSK, NKSF1, P35	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	C00023672
3593	IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	C00023672
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00023672
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00023672
51561	IL23A, IL-23, IL-23A, IL23P19, P19, SGRF	interleukin 23, alpha subunit p19	C00023672
3562	IL3, IL-3, MCGF, MULTI-CSF	interleukin 3 (colony-stimulating factor, multiple)	C00023672
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00023672
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00023672
3685	ITGAV, CD51, MSK8, VNRA, VTNR	integrin, alpha V	C00023672
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00023672
3690	ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	C00023672
3756	KCNH1, EAG, EAG1, Kv10.1, h-eag	potassium voltage-gated channel, subfamily H (eag-related), member 1	C00023672
3978	LIG1	ligase I, DNA, ATP-dependent (EC:6.5.1.1)	C00023672
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00023672
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00023672
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00023672
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00023672
406991	MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21	microRNA 21	C00023672
4321	MMP12, HME, ME, MME, MMP-12	matrix metallopeptidase 12 (macrophage elastase) (EC:3.4.24.65)	C00023672
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00023672
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00023672
4504	MT3, GIF, GIFB, GRIF, ZnMT3	metallothionein 3	C00023672
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00023672
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00023672
4613	MYCN, MODED, MYCNOT, N-myc, NMYC, ODED, bHLHe37	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	C00023672
58498	MYL7, MYL2A, MYLC2A	myosin, light chain 7, regulatory	C00023672
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00023672
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00023672
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00023672
2516	NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3	nuclear receptor subfamily 5, group A, member 1	C00023672
4922	NTS, NMN-125, NN, NT, NT/N, NTS1	neurotensin	C00023672
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00023672
27250	PDCD4, H731	programmed cell death 4 (neoplastic transformation inhibitor)	C00023672
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00023672
5290	PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (EC:2.7.11.1 2.7.1.153)	C00023672
5291	PIK3CB, P110BETA, PI3K, PI3KBETA, PIK3C1	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta (EC:2.7.1.153)	C00023672
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00023672
10761	PLAC1, CT92, OOSP2L	placenta-specific 1	C00023672
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00023672
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00023672
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00023672
5731	PTGER1, EP1	prostaglandin E receptor 1 (subtype EP1), 42kDa	C00023672
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00023672
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00023672
5829	PXN	paxillin	C00023672
5887	RAD23B, HHR23B, HR23B, P58	RAD23 homolog B (S. cerevisiae)	C00023672
10111	RAD50, NBSLD, RAD502, hRad50	RAD50 homolog (S. cerevisiae)	C00023672
5906	RAP1A, KREV-1, KREV1, RAP1, SMGP21	RAP1A, member of RAS oncogene family	C00023672
6194	RPS6, S6	ribosomal protein S6	C00023672
6199	RPS6KB2, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb	ribosomal protein S6 kinase, 70kDa, polypeptide 2 (EC:2.7.11.1)	C00023672
7857	SCG2, CHGC, EM66, SN, SgII	secretogranin II	C00023672
871	SERPINH1, AsTP3, CBP1, CBP2, HSP47, OI10, PPROM, RA-A47, SERPINH2, gp46	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	C00023672
140885	SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP	signal-regulatory protein alpha (EC:3.1.3.48)	C00023672
23411	SIRT1, SIR2L1	sirtuin 1	C00023672
6528	SLC5A5, NIS, TDH1	solute carrier family 5 (sodium/iodide cotransporter), member 5	C00023672
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00023672
6667	SP1	Sp1 transcription factor	C00023672
412	STS, ARSC, ARSC1, ASC, ES, SSDD, XLI	steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2)	C00023672
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00023672
7082	TJP1, ZO-1	tight junction protein 1	C00023672
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00023672
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00023672
7161	TP73, P73	tumor protein p73	C00023672
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00023672
7520	XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	C00023672
2547	XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	C00023672
10413	YAP1, YAP, YAP2, YAP65, YKI	Yes-associated protein 1	C00023672
7702	ZNF143, SBF, STAF, pHZ-1	zinc finger protein 143	C00023672

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