| class name | count |
|---|---|
| eudicotyledons | 5 |
| asterids | 1 |
| class name | count |
|---|---|
| Cactaceae | 3 |
| Acanthaceae | 1 |
| Amaranthaceae | 1 |
| Plumbaginaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001334
|
beta-Alaninebetaine
|
|
||||
|
C00007291
|
Betaine
|
CHEMBL95889
CHEMBL1182 |
D001622
|
10 / 5 / 5 | 4 / 11 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00007291 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00007291 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00007291 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00007291 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00007291 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007291 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00007291 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00007291 | 0 / 1 |
| Q7Z2H8 | Proton-coupled amino acid transporter 1 | Unclassified protein | C00007291 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00007291 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 635 | BHMT, BHMT1 | betaine--homocysteine S-methyltransferase (EC:2.1.1.5) |
C00007291
|
| 2157 | F8, AHF, DXS1253E, F8B, F8C, FVIII, HEMA | coagulation factor VIII, procoagulant component |
C00007291
|
| 2158 | F9, FIX, HEMB, P19, PTC, THPH8 | coagulation factor IX (EC:3.4.21.22) |
C00007291
|
| 6584 | SLC22A5, CDSP, OCTN2, OCTN2VT | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
C00007291
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D003711 | Demyelinating Diseases |
C00007291
|
| D056486 | Drug-Induced Liver Injury |
C00007291
|
| D005235 | Fatty Liver, Alcoholic |
C00007291
|
| D006712 | Homocystinuria |
C00007291
|
| D008106 | Liver Cirrhosis, Experimental |
C00007291
|
| D008113 | Liver Neoplasms |
C00007291
|
| D008569 | Memory Disorders |
C00007291
|
| D008661 | Metabolism, Inborn Errors |
C00007291
|
| D009203 | Myocardial Infarction |
C00007291
|
| D009436 | Neural Tube Defects |
C00007291
|
| D013610 | Tachycardia |
C00007291
|