class name | count |
---|---|
rosids | 17 |
class name | count |
---|---|
Rutaceae | 17 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00001745
![]() |
Mahanimbine
|
CHEMBL495873
|
3 / 7 / 10 |
![]() |
||
C00024680
![]() |
7-Methoxymurrayacine
|
CHEMBL1689803
|
![]() |
|||
C00024704
![]() |
Eustifoline B
|
![]() |
||||
C00024709
![]() |
Glycomaurine
/ Eustifoline-A |
![]() |
||||
C00024713
![]() |
Isomahanine
|
CHEMBL498436
|
20 / 19 / 21 |
![]() |
||
C00024719
![]() |
Mukonicine
|
![]() |
||||
C00024746
![]() |
NSC 654283
/ Pyrayafoline B |
CHEMBL495872
|
![]() |
|||
C00024747
![]() |
Pyrayafoline C
|
![]() |
||||
C00024748
![]() |
Pyrayafoline D
|
CHEMBL498436
|
20 / 19 / 21 |
![]() |
||
C00024749
![]() |
Pyrayafoline E
|
![]() |
||||
C00025171
![]() |
NSC 94932
/ Girinimbin / Girinimbine |
CHEMBL1477760
|
C034052
|
16 / 17 / 43 |
![]() |
|
C00028618
![]() |
Murrayamine I
|
![]() |
||||
C00028619
![]() |
Murrayamine J
|
![]() |
||||
C00028620
![]() |
Murrayamine K
|
![]() |
||||
C00028622
![]() |
Murrayamine N
|
![]() |
||||
C00044783
![]() |
Glycoborinine
|
CHEMBL506671
|
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10636 | Microtubule-associated protein tau | Unclassified protein | C00001745 C00024713 C00024748 C00025171 | 4 / 3 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001745 C00024713 C00024748 | 1 / 2 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00024713 C00024748 C00025171 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00024713 C00024748 C00025171 | 0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00024713 C00024748 C00025171 | 0 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00024713 C00024748 C00025171 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00001745 C00024713 C00024748 | 2 / 5 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00024713 C00024748 C00025171 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00024713 C00024748 C00025171 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00024713 C00024748 C00025171 | 2 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00024713 C00024748 | 0 / 0 |
P37840 | Alpha-synuclein | Unclassified protein | C00024713 C00024748 | 4 / 2 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00024713 C00024748 | 1 / 0 |
Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00024713 C00024748 | 1 / 4 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00024713 C00024748 | 1 / 1 |
Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00024713 C00024748 | 0 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00024713 C00024748 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00024713 C00024748 | 1 / 1 |
P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00024713 C00024748 | 0 / 3 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00024713 C00024748 | 1 / 0 |
P11308 | Transcriptional regulator ERG | Unclassified protein | C00025171 | 1 / 2 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | C00025171 | 1 / 1 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025171 | 0 / 0 |
P51151 | Ras-related protein Rab-9A | Unclassified protein | C00025171 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00025171 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00025171 | 0 / 0 |
P17861 | X-box-binding protein 1 | Unclassified protein | C00025171 | 1 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00025171 | 7 / 37 |
OMIM | preferred title | UniProt |
---|---|---|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#208900 | Ataxia-telangiectasia; at |
Q13315
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#114500 | Colorectal cancer; crc |
P84022
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#133239 | Esophageal cancer |
P04637
|
#612219 | Ewing sarcoma; es |
P11308
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P04637
|
#612371 | Major affective disorder 7; mafd7 |
P17861
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P37840
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
H00082 | Graves' disease |
P01215
(marker)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
Q13315 (related) |
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
|
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00024 | Prostate cancer |
P11308
(related)
|
H00035 | Ewing's sarcoma |
P11308
(related)
|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
H00094 | DNA repair defects |
Q13315
(related)
|
H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|