PCIDB

KNApSAcK Metabolite C00001745

Metabolite

KNApSAcK Entry

id C00001745
Name Mahanimbine
CAS RN 21104-28-9
Standard InChI InChI=1S/C23H25NO/c1-15(2)8-7-12-23(4)13-11-18-21-19(14-16(3)22(18)25-23)17-9-5-6-10-20(17)24-21/h5-6,8-11,13-14,24H,7,12H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C23H25NO/c1-15(2)8-7-12-23(4)13-11-18-21-19(14-16(3)22(18)25-23)17-9-5-6-10-20(17)24-21/h5-6,8-11,13-14,24H,7,12H2,1-4H3

Cluster

Phytochemical cluster
KCF-S cluster No. 516

Link

ChEMBL

By standard InChI CHEMBL495873
By standard InChI Main Layer CHEMBL495873

KEGG

By LinkDB C09220

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Rutaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Murraya exotica 159059 Rutaceae rosids Viridiplantae
Murraya koenigii 159030 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL495873 CHEMBL1614421 (1) CHEMBL1614502 (1)
4 / 3
O00255 Menin Unclassified protein CHEMBL495873 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL495873 CHEMBL1614257 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (10)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)